🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

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Identification of polycystin 2 missense mutants targeted for endoplasmic reticulum-associated degradation

American Journal of Physiology-Cell Physiology(2024)10.1152/ajpcell.00776.2024Source: DataRank Database

Identification of polycystin 2 missense mutants targeted for endoplasmic reticulum-associated degradation is a research paper published in American Journal of Physiology-Cell Physiology (2024). On theSindex it has a DataRank of 0. It has been cited 4 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

Cite:

Linked data & code

rrid

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (19 grants)Impact (FWCI 1.54)OA: hybridTopics (43)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Marcelo D. Carattino ORCID,Katherine G. Sharp ORCID,Luke J. Kantz,Nikolay Gresko,Michael J. Caplan ORCID

Live enrichment

PubMed:39714991 PMC:PMC12168846 OpenAlex:https://openalex.org/W4405707913

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: U24DK126110

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK079307

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK137329

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK124659

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK137149

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK119183

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK134431

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK125034

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: U54 DK126114

HHS | NIH | National Institute of General Medical Sciences

Grant: 131732

NSF | National Science Foundation Graduate Research Fellowship Program

Grant: 2139321

U.S. Department of Defense

Grant: PR191158

NIDDK NIH HHS

Grant: R03 DK124659

NIDDK NIH HHS

Grant: R01 DK119183

NIDDK NIH HHS

Grant: R21 DK137149

NIDDK NIH HHS

Grant: P30 DK079307

NIDDK NIH HHS

Grant: U54 DK137329

NIDDK NIH HHS

Grant: R01 DK134431

NIGMS NIH HHS

Grant: R35 GM131732

FWCI

1.54

Citation Percentile

0.8%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1152/ajpcell.00776.2024

publisherhttps://doi.org/10.1152/ajpcell.00776.2024

publisherhttps://journals.physiology.org/doi/pdf/10.1152/ajpcell.00776.2024

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39714991

https://www.ncbi.nlm.nih.gov/pmc/articles/12168846

Fields of Study

Genetic and Kidney Cyst DiseasesBiomedical Research and PathophysiologyMicrotubule and mitosis dynamicsTRPP Cation ChannelsHumansMutation, MissenseHEK293 CellsEndoplasmic Reticulum-Associated DegradationPolycystic Kidney, Autosomal DominantSaccharomyces cerevisiaeUbiquitinationProtein FoldingEndoplasmic ReticulumProteasome Endopeptidase Complex

MeSH Terms

Endoplasmic ReticulumHumansSaccharomyces cerevisiaePolycystic Kidney, Autosomal DominantProtein FoldingMutation, MissenseProteasome Endopeptidase ComplexTRPP Cation ChannelsUbiquitinationHEK293 CellsProteolysisEndoplasmic Reticulum-Associated Degradation

Keywords

Endoplasmic-reticulum-associated protein degradationMissense mutationEndoplasmic reticulumBiologyCell biologyPKD1MutantHEK 293 cellsProtein degradationMutationGeneticsAutosomal dominant polycystic kidney diseaseUnfolded protein responseGeneEndoplasmic Reticulum-associated Degradation (Erad)Autosomal Dominant Polycystic Kidney Disease (Adpkd)Polycystin 2 (Pc2)

Sustainable Development Goals

SDG 0: Good health and well-being