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Treg-specific IL-6R signaling: a novel role in the regulation of the intestinal epithelium

American Journal of Physiology-Gastrointestinal and Liver Physiology(2025)10.1152/ajpgi.00131.2025Source: DataRank Database

Treg-specific IL-6R signaling: a novel role in the regulation of the intestinal epithelium is a research paper published in American Journal of Physiology-Gastrointestinal and Liver Physiology (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (6 grants)Impact (FWCI 0.00)OA: hybridTopics (62)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (17)

Feda H. Hamdan ORCID,Isaiah Pérez ORCID,Hannah M. Smith ORCID,Kimberlee Kossick ORCID,Yaroslav Fedyshyn ORCID

Live enrichment

PubMed:40820933 PMC:PMC12724081 OpenAlex:https://openalex.org/W4413288603

HHS | National Institutes of Health

Grant: R01AI089 714-022

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: T32DK007198

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: P30DK084567

AGA Research Foundation

Grant: Research Scholar Award

NIDDK NIH HHS

Grant: K01 DK124358

NIAID NIH HHS

Grant: R01 AI089714

FWCI

0.00

Citation Percentile

0.2%

hybridLicense: cc-by

journalhttps://journals.physiology.org/doi/pdf/10.1152/ajpgi.00131.2025

publisherhttps://journals.physiology.org/doi/pdf/10.1152/ajpgi.00131.2025

journalhttps://doi.org/10.1152/ajpgi.00131.2025

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40820933

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12724081/

Fields of Study

Microscopic ColitisImmune Cell Function and InteractionT-cell and B-cell ImmunologyAnimalsReceptors, Interleukin-6T-Lymphocytes, RegulatoryIntestinal MucosaSignal TransductionHumansMice, KnockoutMiceColitisInterleukin-6Dextran SulfateOrganoidsMice, Inbred C57BLDisease Models, AnimalInflammatory Bowel Diseases

MeSH Terms

AnimalsColitisDisease Models, AnimalHumansIntestinal MucosaMice, Inbred C57BLOrganoidsInflammatory Bowel DiseasesSignal TransductionInterleukin-6Dextran SulfateMice, KnockoutReceptors, Interleukin-6T-Lymphocytes, RegulatoryMice

Keywords

Conditional gene knockoutIntestinal epitheliumColitisImmunologyAdoptive cell transferInterleukin 22Immune systemKnockout mouseInflammatory bowel diseaseBiologyInflammationIntestinal mucosaDownregulation and upregulationSignal transductionCell biologyEpitheliumCancer researchInterleukinCytokineReceptorT cellMedicinePhenotypeInternal medicineDiseaseGeneIntestinal epithelial cellsIL-6RTregs

Sustainable Development Goals

SDG 0: Good health and well-being

Treg-specific IL-6R signaling: a novel role in the regulation of the intestinal epithelium

FAIR Checklist

Authors (17)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)