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DNMT3A R882H Is Not Required for Disease Maintenance in Primary Human AML but Is Associated with Increased Leukemia Stem Cell Frequency

Cancer Discovery(2025)10.1158/2159-8290.cd-24-1604Source: DataRank Database

DNMT3A R882H Is Not Required for Disease Maintenance in Primary Human AML but Is Associated with Increased Leukemia Stem Cell Frequency is a research paper published in Cancer Discovery (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (32 grants)Impact (FWCI 1.63)OA: greenTopics (21)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (18)

Daiki Karigane ORCID,Eleanor Hilgart ORCID,Amy C. Fan ORCID,Kensuke Kayamori ORCID,Masashi Miyauchi ORCID

Live enrichment

PubMed:41263425 PMC:PMC12717831 OpenAlex:https://openalex.org/W4416414507

Deutsche Forschungsgemeinschaft

Grant: KO 5509/1-1

American Society of Hematology

Grant: Research Restart Award

Leukemia and Lymphoma Society

Grant: 3406-21

Japan Society for the Promotion of Science

Grant: JP21J01690

National Science Foundation

Grant: Graduate Research Fellowship Program

National Institutes of Health

Grant: DP5OD024558

National Cancer Institute

Grant: 5R01CA054358

National Cancer Institute

Grant: 1R01CA251331

Leukemia and Lymphoma Society

Grant: Blood Cancer Discoveries Grant Program

NCI NIH HHS

Grant: R01 CA054358

NCI NIH HHS

Grant: R01 CA288731

NCI NIH HHS

Grant: R01 CA251331

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

National Institutes of Health

Grant: 2R01CA054358-20A1

Epigenetic Drivers of Cancer Progression

National Institutes of Health

Grant: 5DP5OD024558-02

Developing approaches for universal organ transplantation

National Institutes of Health

Grant: 5R01CA251331-02

Human Acute Myeloid Leukemia Stem Cells

David and Lucile Packard Foundation

National Defense Science and Engineering Graduate

Pew Charitable Trusts

David and Lucile Packard Foundation (PF)

Human Frontier Science Program

Pew Charitable Trusts (Pew)

Paul G. Allen Frontiers Group

Paul G. Allen Frontiers Group (The Frontiers Group)

National Defense Science and Engineering Graduate (NDSEG)

Mark Foundation For Cancer Research

Nakayama Foundation for Human Science ()

Human Frontier Science Program (HFSP)

Nakayama Foundation for Human Science

Stanford Lieberman Fellowship

Stanford Ludwig Center for Cancer Stem Cell Research and Medicine

Mark Foundation For Cancer Research (Mark Foundation)

FWCI

1.63

Citation Percentile

0.9%

Citation Trend

2026

greenLicense: CC BY

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12717831/

publisherhttps://aacrjournals.org/cancerdiscovery/article-pdf/doi/10.1158/2159-8290.CD-24-1604/3672646/cd-24-1604.pdf

publisherhttps://aacrjournals.org/cancerdiscovery/article-pdf/doi/10.1158/2159-8290.CD-24-1604/3733242/cd-24-1604.pdf

publisherhttps://aacrjournals.org/cancerdiscovery/article-pdf/16/3/592/3740969/cd-24-1604.pdf

Fields of Study

Acute Myeloid Leukemia ResearchCancer Genomics and DiagnosticsEpigenetics and DNA Methylation0303 health sciences03 medical and health sciences

MeSH Terms

DNA Methyltransferase 3AAnimalsDNA (Cytosine-5-)-MethyltransferasesHumansNeoplastic Stem CellsLeukemia, Myeloid, AcuteDNA MethylationMutation, MissenseMice

Keywords

LeukemiaMutationDiseaseStem cellCancerMyeloid leukemiaArticle

DNMT3A R882H Is Not Required for Disease Maintenance in Primary Human AML but Is Associated with Increased Leukemia Stem Cell Frequency

FAIR Checklist

Authors (18)

Funding (32 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)