Immunocytochemical Localization of Insulin-Like Growth Factor I in the Hypothalamo-Hypophyseal System of the Adult Rat is a research paper published in Neuroendocrinology (2008). On theSindex it has a DataRank of 0.875. It has been cited 16 times, with 13 citing works in its 1-hop citation network.
Insulin-like growth factor I (IGF-I) is shown to be involved in the regulation of pituitary hormones. High IGF-I concentrations were detected in hypothalamus and pituitary during adulthood. This study was undertaken to analyze the cellular distribution of IGF-I in the hypothalamo-hypophyseal system of the adult rat using immunocytochemical procedures. IGF-I was found to be widely distributed throughout the hypothalamus; it was present in the magnocellular neurons of the supraoptic, paraventricular, and accessory nuclei. Moreover, nerve fibres and puncta containing immunoreactive IGF-I were localized in the median eminence and the posterior lobe of the pituitary. These results support possible IGF-I neuromodulatory or neurohormonal action in the hypothalamus on pituitary hormone regulation.
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Base Score Contribution
0.425
From this paper's citation signal
Citation Network Contribution
0.450
From 12 citing papers with measurable signal
DataRank blends this paper's own citation count with the influence of the papers that cite it. Here, roughly 49% comes from its base citations and 51% from the citation network (12 citing papers contributed measurable signal).
Citers are pulled from OpenAlex sorted by cited_by_count:descand capped per paper, so when the cap binds we keep the highest-signal references and the score is reproducible across reruns.
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