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Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization

Circulation Genomic and Precision Medicine(2024)10.1161/circgen.123.004272Source: DataRank Database

Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization is a research paper published in Circulation Genomic and Precision Medicine (2024). On theSindex it has a DataRank of 0.917. It has been cited 39 times, with 35 citing works in its 1-hop citation network.

N/A

0.917DataRank · unranked

Scored on demand from live citation data

Open Access39 citations · 35 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (20 grants)Impact (FWCI 13.99)OA: greenTopics (54)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 60%Citation Network 40%

Base Score Contribution

0.553

From this paper's citation signal

Citation Network Contribution

0.363

From 19 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 35 citers.

Enhancing the Prediction Power of Polygenic Risk Scores in Genetically Diverse Coronary Heart Disease
Circulation Genomic and Precision Medicine20241 citations10 referencesContributes 0.069
Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations
Nature Genetics202518 citations54 referencesContributes 0.055
Insights into Ancestral Diversity in Parkinson’s Disease Risk: A Comparative Assessment of Polygenic Risk Scores
medRxiv20235 citations38 referencesContributes 0.047
Population-specific polygenic risk scores for people of Han Chinese ancestry
Nature202516 citations81 referencesContributes 0.035
Polygenic Risk Scores and Coronary Artery Disease
Cardiogenetics20253 citations44 referencesContributes 0.032

Authors (19)

Catherine Tcheandjieu ORCID,Ozan Dikilitas ORCID,Kruthika Iyer ORCID,Kazuo Miyazawa ORCID,Austin T. Hilliard ORCID

Live enrichment

PubMed:38380516 OpenAlex:https://openalex.org/W4392015588

National Institutes of Health

Grant: 5K24HL137010-04

Patient-Oriented Research in Genomic Discovery and Implementation

National Institutes of Health

Grant: 3U01HG006379-12S3

EHR-based Genomic Discovery and Implementation (Supplement)

National Institutes of Health

Grant: 2R01HL105756-07

CHARGE consortium: gene discovery for CVD and aging phenotypes

National Institutes of Health

Grant: 5UM1DK078616-16

TOPMed Omics of Type 2 Diabetes and Quantitative Traits

National Institutes of Health

Grant: 5R01HL151855-02

TOPMed Omics of Cardiovascular Disease in Diabetes

National Institutes of Health

Grant: 5R35GM140487-05

Quantitative Methods for Genetic Epidemiology

National Institutes of Health

Grant: 5U01HG011710-05

Polygenic Risk of Disease in Populations of Diverse Ancestry

National Institutes of Health

Grant: 5R01HL146860-02

Whole-genome sequencing analysis of coronary atherosclerosis and related traits

NHLBI NIH HHS

Grant: K24 HL137010

NHLBI NIH HHS

Grant: R01 HL105756

NHLBI NIH HHS

Grant: R01 HL146860

NHGRI NIH HHS

Grant: R01 HG011432

NHGRI NIH HHS

Grant: U01 HG011710

NHGRI NIH HHS

Grant: U01 HG006379

NHLBI NIH HHS

Grant: R01 HL151152

NIGMS NIH HHS

Grant: R35 GM140487

NHGRI NIH HHS

Grant: U24 HG009650

NHGRI NIH HHS

Grant: U41 HG009650

NHLBI NIH HHS

Grant: R01 HL151855

NIDDK NIH HHS

Grant: UM1 DK078616

FWCI

13.99

Citation Percentile

1.0%

Citation Trend

2023

2024

2025

2026

greenLicense: other-oa

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11372723/pdf/nihms-1987352.pdf

publisherhttps://www.ahajournals.org/doi/full/10.1161/CIRCGEN.123.004272

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11372723

journalhttps://doi.org/10.1161/circgen.123.004272

Fields of Study

Genetic Associations and EpidemiologyLiver Disease Diagnosis and TreatmentFolate and B Vitamins Research0301 basic medicine03 medical and health sciencesHumansGenome-Wide Association StudyCoronary DiseaseMultifactorial InheritanceMaleFemaleGenetic Predisposition to DiseasePolymorphism, Single NucleotideRisk FactorsMiddle AgedGenetic Risk Score

MeSH Terms

Genetic Risk ScoreCoronary DiseaseFemaleHumansMaleMiddle AgedRisk FactorsGenetic Predisposition to DiseaseMultifactorial InheritancePolymorphism, Single NucleotideGenome-Wide Association Study

Keywords

Genome-wide association studyPolygenic risk scoreCoronary heart diseasePopulationGeneticsBiologyGenetic associationMedicineInternal medicineSingle-nucleotide polymorphismGenotypeGeneEnvironmental healthMaleMultifactorial InheritanceCoronary DiseaseMiddle AgedPolymorphism, Single NucleotideArticleRisk FactorsHumansFemaleGenetic Predisposition to DiseaseGenetic Risk Scoregenetic association studiesgenetic variationodds ratio

Sustainable Development Goals

SDG 0: Good health and well-being