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Programming to S1PR1 + Endothelial Cells Promotes Restoration of Vascular Integrity

Circulation Research(2021)10.1161/circresaha.120.318412Source: DataRank Database

Programming to S1PR1 + Endothelial Cells Promotes Restoration of Vascular Integrity is a research paper published in Circulation Research (2021). On theSindex it has a DataRank of 1.4. It has been cited 44 times, with 36 citing works in its 1-hop citation network.

N/A

1.4DataRank · unranked

Scored on demand from live citation data

Open Access44 citations · 36 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (12 grants)Impact (FWCI 2.59)OA: bronzeTopics (90)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 40%Citation Network 60%

Base Score Contribution

0.571

From this paper's citation signal

Citation Network Contribution

0.864

From 30 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 36 citers.

Recuperation of Vascular Homeostasis
Circulation Research20217 citations12 referencesContributes 0.173
Early Growth Response‐1, an Integrative Sensor in Cardiovascular and Inflammatory Disease
Journal of the American Heart Association202167 citations54 referencesContributes 0.078
Sphingosine-1-Phosphate Receptor 3 Induces Endothelial Barrier Loss via ADAM10-Mediated Vascular Endothelial-Cadherin Cleavage
International Journal of Molecular Sciences202313 citations38 referencesContributes 0.069
Targeting Rho kinase to restore endothelial barrier function following vascular scaffold implantation
Drug Discovery Today20238 citations40 referencesContributes 0.055
Rewiring Endothelial Sphingolipid Metabolism to Favor S1P Over Ceramide Protects From Coronary Atherosclerosis
Circulation Research202429 citations66 referencesContributes 0.052

Authors (7)

Jagdish Chandra Joshi ORCID,Vijay Avin Balaji Ragunathrao ORCID,Mark Maienschein‐Cline ORCID,Richard L. Proia ORCID,Asrar B. Malik ORCID

Live enrichment

PubMed:33926208 PMC:PMC8273089 OpenAlex:https://openalex.org/W3159287587

HHS | National Institutes of Health

Grant: HL060678

HHS | National Institutes of Health

Grant: HL137169

HHS | National Institutes of Health

Grant: HL084153

American Heart Association

Grant: 19POST34450241

NHLBI NIH HHS

Grant: P01 HL060678

NHLBI NIH HHS

Grant: R01 HL084153

NHLBI NIH HHS

Grant: R01 HL137169

NCATS NIH HHS

Grant: UL1 TR002003

National Institutes of Health

Grant: 5P01HL060678-07

G Protein Regulation of Endothelial Barrier Function

National Institutes of Health

Grant: 5R01HL084153-07

Focal adhesion kinase regulation of lung vascular permeability and edemagenesis

National Institutes of Health

Grant: 5R01HL137169-04

Mechanisms of endothelial regeneration and resolution of lung vascular injury

National Institutes of Health

Grant: 5UL1TR002003-08

Clinical and Translational Science Award

FWCI

2.59

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

bronze

journalhttps://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.120.318412

publisherhttps://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.120.318412

publisherhttps://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.120.318412

journalhttps://doi.org/10.1161/circresaha.120.318412

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33926208

Fields of Study

Sphingolipid Metabolism and SignalingATP Synthase and ATPases ResearchIon Transport and Channel Regulation0301 basic medicine03 medical and health sciencesAcute Lung InjuryAnimalsAnion Transport ProteinsCapillary PermeabilityCell LineageCell ProliferationCells, CulturedDisease Models, AnimalEndothelial CellsEndotoxemiaGreen Fluorescent ProteinsHumansLungLysophospholipidsMice, KnockoutPhenotypePhosphotransferases (Alcohol Group Acceptor)RegenerationSTAT3 Transcription FactorSignal TransductionSphingosineSphingosine-1-Phosphate ReceptorsMiceSphingosine Kinase

MeSH Terms

Sphingosine-1-Phosphate ReceptorsSphingosine KinaseAnimalsCapillary PermeabilityCells, CulturedDisease Models, AnimalHumansLungLysophospholipidsPhenotypeRegenerationSphingosineSignal TransductionPhosphotransferases (Alcohol Group Acceptor)Mice, KnockoutCell LineageEndotoxemiaAnion Transport ProteinsEndothelial CellsCell ProliferationGreen Fluorescent ProteinsSTAT3 Transcription FactorMiceAcute Lung Injury

Keywords

S1PR1Cell biologySphingosinePopulationBiologySphingosine-1-phosphateVascular permeabilityEndothelial stem cellImmunologyVascular endothelial growth factor ACancer researchReceptorMedicineVascular endothelial growth factorEndocrinologyBiochemistryPermeabilityAcute Lung InjuryEndothelial CellsMice, KnockoutSTAT3 Transcription FactorAnion Transport ProteinsGreen Fluorescent ProteinsEndotoxemiaCapillary PermeabilityDisease Models, AnimalPhosphotransferases (Alcohol Group Acceptor)PhenotypeAnimalsHumansRegenerationCell LineageLysophospholipidsLungCells, CulturedCell ProliferationSignal Transduction

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 0: Life in Land