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BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes

Circulation(2020)10.1161/circulationaha.120.047753Source: DataRank Database

BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes is a research paper published in Circulation (2020). On theSindex it has a DataRank of 0. It has been cited 54 times.

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Open Access54 citations

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Enrichment:Funding (16 grants)Impact (FWCI 2.44)OA: bronzeTopics (95)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (3)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (19)

Michael Alexanian ORCID,Ricardo Linares-Saldana ORCID,Bárbara González‐Terán ORCID,Gaia Andreoletti ORCID,Yu Huang ORCID

Live enrichment

PubMed:33094644 PMC:PMC7736290 OpenAlex:https://openalex.org/W3093674907

NHLBI NIH HHS

Grant: P01 HL089707

NCRR NIH HHS

Grant: C06 RR018928

NHLBI NIH HHS

Grant: F31 HL147416

NHLBI NIH HHS

Grant: R01 HL057181

NHLBI NIH HHS

Grant: R01 HL127240

NHLBI NIH HHS

Grant: R01 HL139783

Swiss National Science Foundation

Grant: 186704

Targeting Enhancer-Signaling in Cardiac Fibrosis and Heart Failure Pathogenesis

NHLBI NIH HHS

Grant: P01 HL146366

National Institutes of Health

Grant: 5R01HL057181-25

Cardiogenesis: Molecular Mechanisms

National Institutes of Health

Grant: 5P01HL146366-04

Combinatorial Regulation of Gene Networks During Cardiac Development and Disease

National Institutes of Health

Grant: 5R01HL139783-03

The Role of BRD4 in Cardiac Specification

National Institutes of Health

Grant: 1R01HL127240-01

Regulation of Chromatin Signaling in Heart Failure by BET Bromodomain Proteins

Swiss National Science Foundation

Grant: 147416

Quecksilber in der Medizin: Fluide Wissens- und Handelsökonomien

Fundação para a Ciência e a Tecnologia, I.P.

Grant: PTDC/CCI-INF/6762/2020

MS3: New foundations for micro-services and serverless systems

National Institutes of Health

Grant: 1C06RR018928-01

EXTRAMULAR RESEARCH FACILITIES CONSTRUCTION

National Institutes of Health

Grant: 5F31HL147416-03

Defining the role of HOPX and genome-nuclear lamina interactions in cardiomyocyte commitment

FWCI

2.44

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronze

journalhttps://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.120.047753?download=true

publisherhttps://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.120.047753?download=true

publisherhttps://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.120.047753

journalhttps://doi.org/10.1161/circulationaha.120.047753

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33094644

Fields of Study

Protein Degradation and InhibitorsChromatin Remodeling and CancerGenomics and Chromatin Dynamics0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaBromodomain Containing ProteinsAnimalsEnergy MetabolismGene Expression RegulationGenotypeHomeostasisHumansMice, Inbred C57BLMitochondria, HeartNuclear ProteinsPhenotypeProtein BindingTranscription FactorsVentricular Function, LeftRats, Sprague-DawleyMice, KnockoutVentricular Dysfunction, LeftGene Expression ProfilingMyocytes, CardiacGATA4 Transcription FactorHEK293 CellsTranscriptome

Keywords

BRD4BromodomainTranscription factorCell biologyBiologyChromatinCoactivatorGATA4EpigeneticsEpigenomicsRegulation of gene expressionGeneticsGeneGene expressionDNA methylationMitochondriaMyocytes, cardiacLeftCardiorespiratory Medicine and HaematologyInbred C57BLCardiovascularMitochondria, HeartRats, Sprague-DawleyMiceVentricular DysfunctionVentricular Function2.1 Biological and endogenous factorsHomeostasisAetiologyMice, Knockoutprasugrel hydrochlorideNuclear ProteinsHeartPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaHeart DiseasePhenotypePublic Health and Health ServiceshemorrhageCardiacBiotechnologyProtein BindingGenotypeKnockout1.1 Normal biological development and functioningClinical SciencesticagrelorUnderpinning researchAnimalsHumansthrombosisMyocytesGene Expression ProfilingHuman Genomepercutaneous coronary interventionmortalityRatsGATA4 Transcription FactorMice, Inbred C57BLST elevation myocardial infarctionHEK293 CellsCardiovascular System & HematologyGene Expression RegulationSprague-DawleyEnergy MetabolismTranscriptomeTranscription Factors

Sustainable Development Goals

SDG 3: 3. Good healthSDG 7: 7. Clean energySDG 0: Affordable and clean energy