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Unfolded Protein Response as a Compensatory Mechanism and Potential Therapeutic Target in PLN R14del Cardiomyopathy

Circulation(2021)10.1161/circulationaha.120.049844Source: DataRank Database

Unfolded Protein Response as a Compensatory Mechanism and Potential Therapeutic Target in PLN R14del Cardiomyopathy is a research paper published in Circulation (2021). On theSindex it has a DataRank of 0. It has been cited 76 times.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (23 grants)OA: bronzeTopics (62)IDs (PubMed, PMC)SDGs (2)

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Authors (22)

Isaac Perea‐Gil ORCID,Renée G. C. Maas ORCID,Magdaléna Harakaľová ORCID,Alexandra A. Gavidia ORCID,Jennifer Arthur Ataam ORCID

Live enrichment

PubMed:33928785 PMC:PMC8667423

NHLBI NIH HHS

Grant: R01 HL128072

NHLBI NIH HHS

Grant: R01 HL130840

NHLBI NIH HHS

Grant: R01 HL132225

Dutch Research Council (NWO)

Grant: 016.176.136

American Heart Association-American Stroke Association

Grant: 17IRG33410532

American Heart Association-American Stroke Association

Grant: 19POST34380920

NHLBI NIH HHS

Grant: P01 HL141084

NHLBI NIH HHS

Grant: R01 HL139679

ZonMw

Grant: 116006102

NHLBI NIH HHS

Grant: R00 HL104002

NHLBI NIH HHS

Grant: R01 HL113006

NHLBI NIH HHS

Grant: R01 HL150414

NIH HHS

Grant: S10 OD030264

National Institutes of Health

Grant: 1R01HL128072-01

Role of miR25 in Heart Failure

Fundação para a Ciência e a Tecnologia, I.P.

Grant: PTDC/CCI-INF/6762/2020

MS3: New foundations for micro-services and serverless systems

National Institutes of Health

Grant: 5P01HL141084-04

Elucidating Electro-Mechanical Dysfunction in Heart Failure with Human Stem Cell Models

National Institutes of Health

Grant: 2R01HL113006-06

Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling

National Institutes of Health

Grant: 5R01HL139679-04

Unraveling the pathogenesis of familial dilated cardiomyopathy towards precision medicine

European Commission

Grant: 708459

Cardiac micro-engineered tissue for high-throughput screening

National Institutes of Health

Grant: 5R01HL130840-03

MicroRNA Control of Dilated Cardiomyopathy

National Institutes of Health

Grant: 4R00HL104002-03

miR-152: A Novel Regulator of Diabetic Cardiomyopathy

National Institutes of Health

Grant: 5R01HL132225-04

Small Molecule NOTCH Inhibitors for the treatment of pulmonary hypertension

European Commission

Grant: 725229

Extracellular Vesicle-Inspired CArdiac Repair

bronzeLicense: other-oa

publisherhttps://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.120.049844

publisherhttps://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.120.049844

repositoryhttps://research.rug.nl/en/publications/53ce900f-a727-4f43-856f-e44f401904b9

repositoryhttps://dspace.library.uu.nl/handle/1874/443010

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8667423

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

HumansCardiomyopathy, DilatedCardiomyopathiesDisease SusceptibilityGenetic Predisposition to DiseaseCalcium-Binding ProteinsCulture Media, ConditionedGene Expression ProfilingAdaptation, PhysiologicalSequence DeletionMyocardial ContractionDisease ManagementUnfolded Protein ResponseInduced Pluripotent Stem CellsMolecular Targeted TherapySingle-Cell AnalysisTranscriptomeBiomarkersPhospholamban

Keywords

Unfolded protein responseModels, BiologicalInduced Pluripotent Stem CellsPhospholambanCardiomyopathy, DilatedSequence Analysis, RnaCardiac & Cardiovascular Systemssequence analysisPROTEOSTASISACTIVATIONmodelsENDOPLASMIC-RETICULUM STRESSHumansGenetic Predisposition to DiseaseMolecular Targeted TherapySequence DeletionScience & TechnologyINDUCTIONGene Expression ProfilingCalcium-Binding ProteinsDisease ManagementMOUSE MODELER STRESSGENEAdaptation, PhysiologicalMyocardial ContractionDIFFERENTIATIONPeripheral Vascular DiseaseCulture Media, ConditionedCardiovascular System & CardiologyRNAHEARTDisease SusceptibilitySingle-Cell AnalysisCardiomyopathiesTranscriptomeLife Sciences & BiomedicinecardiomyopathydilatedbiologicalBiomarkers

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