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Aflibercept, a VEGF (Vascular Endothelial Growth Factor)-Trap, Reduces Vascular Permeability and Stroke-Induced Brain Swelling in Obese Mice

Stroke(2021)10.1161/strokeaha.121.034362Source: DataRank Database

Aflibercept, a VEGF (Vascular Endothelial Growth Factor)-Trap, Reduces Vascular Permeability and Stroke-Induced Brain Swelling in Obese Mice is a research paper published in Stroke (2021). On theSindex it has a DataRank of 0. It has been cited 32 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access32 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 1.63)OA: hybridTopics (68)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

John W. Cave ORCID,Sunghee Cho ORCID,Il‐Doo Kim ORCID

Live enrichment

PubMed:34192895 PMC:PMC8312568 OpenAlex:https://openalex.org/W3176720622

NINDS NIH HHS

Grant: R01 NS103326

NINDS NIH HHS

Grant: R01 NS111568

National Institutes of Health

Grant: 5R01NS111568-02

Immune-mediated mechanisms underlying conditioning-induced stroke recovery

National Institutes of Health

Grant: 5R01NS095359-12

Role of CD36 in functional recovery in chronic stroke

National Institutes of Health

Grant: 5R01NS103326-02

Targeting stroke-induced brain swelling in obese subjects: role of VEGF

FWCI

1.63

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://www.ahajournals.org/doi/pdf/10.1161/STROKEAHA.121.034362?download=true

publisherhttps://www.ahajournals.org/doi/pdf/10.1161/STROKEAHA.121.034362?download=true

publisherhttps://www.ahajournals.org/doi/full/10.1161/STROKEAHA.121.034362

journalhttps://doi.org/10.1161/strokeaha.121.034362

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34192895

Fields of Study

Angiogenesis and VEGF in CancerBarrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms0301 basic medicine03 medical and health sciences0302 clinical medicineAngiogenesis InhibitorsAnimalsBiomarkersBlood-Brain BarrierBrain EdemaCapillary PermeabilityDiet, High-FatFemaleMaleMiceMice, Inbred C57BLObesityReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsStrokeVascular Endothelial Growth Factor A

MeSH Terms

AnimalsBlood-Brain BarrierBrain EdemaCapillary PermeabilityFemaleMaleMice, Inbred C57BLObesityRecombinant Fusion ProteinsBiomarkersStrokeAngiogenesis InhibitorsReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AMiceDiet, High-Fat

Keywords

MedicineVascular endothelial growth factorAfliberceptKinase insert domain receptorVascular permeabilityStroke (engine)Cerebral edemaInternal medicineAnesthesiaEndocrinologyVascular endothelial growth factor APathologyBevacizumabObesityBrain edemaStrokeComorbidityMaleOriginal ContributionsRecombinant Fusion ProteinsAngiogenesis InhibitorsDiet, High-FatCapillary PermeabilityMice, Inbred C57BLMiceReceptors, Vascular Endothelial Growth FactorBlood-Brain BarrierAnimalsFemaleBiomarkers

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 0: Good health and well-being