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Efficacy of AAV9-mediated SGPL1 gene transfer in a mouse model of S1P lyase insufficiency syndrome

JCI Insight(2021)10.1172/jci.insight.145936Source: DataRank Database

Efficacy of AAV9-mediated SGPL1 gene transfer in a mouse model of S1P lyase insufficiency syndrome is a research paper published in JCI Insight (2021). On theSindex it has a DataRank of 0. It has been cited 33 times.

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Open Access33 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)OA: goldTopics (59)IDs (PubMed, PMC)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Gizachew Tassew,Joanna Y. Lee,Babak Oskouian,Denise P. Muñoz ORCID,Jeffrey B. Hodgin ORCID

Live enrichment

PubMed:33755599 PMC:PMC8119223

National Institutes of Health

Grant: NIH S10OD0018070

Swim Across America Foundation

Grant: N/A

NICHD/NIH

Grant: R24HD102061

funding sources listed below remain accurate

Grant: see below

NIH HHS

Grant: S10 OD018070

National Institutes of Health

Grant: 1S10OD018070-01

Agilent 6490 Triple Quadrupole Mass Spectrometer

National Institutes of Health

Grant: 5R24HD102061-02

CRR LIGAND ASSAY AND ANALYSIS CORE

goldLicense: cc-by

publisherhttp://insight.jci.org/articles/view/145936/files/pdf

publisherhttps://insight.jci.org/articles/view/145936/files/pdf

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8119223

repositoryhttps://doaj.org/article/9c9d0a0bbea44c69ba3c08fe8f691e88

Europe_PMChttps://europepmc.org/articles/PMC8119223

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

KidneyAnimalsMice, KnockoutHumansMiceDependovirusNephrotic SyndromeAnemiaMetabolism, Inborn ErrorsHypercholesterolemiaInflammationAldehyde-LyasesCytokinesSurvival RateGene Transfer TechniquesSignal TransductionSTAT3 Transcription FactorGenetic TherapyNeurodevelopmental Disorders

Keywords

Gene therapyMetabolismTherapeuticsGenetic diseasesSTAT3 Transcription Factor570Nephrotic SyndromeIntellectual and Developmental Disabilities (IDD)KnockoutHypercholesterolemia610KidneyMiceRare DiseasesGeneticsAnimalsHumansAldehyde-LyasesPediatricInflammationMice, Knockout5.2 Cellular and gene therapiesInborn ErrorsRGene Transfer TechniquesAnemiaGenetic TherapyDependovirusBrain DisordersSurvival RateNeurodevelopmental DisordersMedicineCytokinesDevelopment of treatments and therapeutic interventionsMetabolism, Inborn ErrorsResearch ArticleSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good health