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Combined heterozygosity of FLT3ITD, TET2, and DNMT3A results in aggressive leukemia

JCI Insight(2022)10.1172/jci.insight.162016Source: DataRank Database

Combined heterozygosity of FLT3ITD, TET2, and DNMT3A results in aggressive leukemia is a research paper published in JCI Insight (2022). On theSindex it has a DataRank of 0. It has been cited 5 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access5 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)Impact (FWCI 0.74)OA: goldTopics (51)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Palam Lakshmi Reddy,Raghuveer Singh Mali ORCID,Santhosh Kumar Pasupuleti ORCID,Ji Zhang ORCID,Mark R. Kelley ORCID

Live enrichment

PubMed:36073548 PMC:PMC9536269 OpenAlex:https://openalex.org/W4294897864

NIH, United States

Grant: R01CA173852,R01CA134777,R01HL146137,R01HL140961,R21CA263470,R21CA263239

NCI NIH HHS

Grant: R21 CA263239

NCI NIH HHS

Grant: R01 CA173852

NCI NIH HHS

Grant: R01 CA244625

NHLBI NIH HHS

Grant: R01 HL146137

NHLBI NIH HHS

Grant: R01 HL140961

NCI NIH HHS

Grant: R01 CA134777

NIGMS NIH HHS

Grant: P20 GM121176

NCI NIH HHS

Grant: R21 CA263470

National Institutes of Health

Grant: 5R01HL146137-03

Targeting Novel Pathways in JMML

National Institutes of Health

Grant: 5R01CA173852-10

Role of p21 activated kinase in Leukemogenesis

National Institutes of Health

Grant: 5R01CA134777-08

Role of Shp2 in FLT3-ITD induced leukemogenesis

National Institutes of Health

Grant: 5R21CA263470-02

Dual anti-leukemic and cardio protective role for ROCK

National Institutes of Health

Grant: 5R21CA263239-02

Novel drug to treat poor prognosis AML

National Institutes of Health

Grant: 1R01HL140961-01A1

Hyperglycemia mediated myeloproliferative disease

FWCI

0.74

Citation Percentile

0.7%

Citation Trend

2023

2024

2025

goldLicense: cc-by

journalhttp://insight.jci.org/articles/view/162016/files/pdf

publisherhttp://insight.jci.org/articles/view/162016/files/pdf

publisherhttps://insight.jci.org/articles/view/162016/files/pdf

journalhttps://doi.org/10.1172/jci.insight.162016

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36073548

Fields of Study

Acute Myeloid Leukemia ResearchMyeloproliferative Neoplasms: Diagnosis and TreatmentCancer Genomics and Diagnostics0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsDNA Methyltransferase 3ADNA-Binding ProteinsDioxygenasesHumansLeukemia, Myeloid, AcuteMiceProto-Oncogene Proteinsfms-Like Tyrosine Kinase 3

MeSH Terms

DNA Methyltransferase 3AAnimalsDNA-Binding ProteinsHumansProto-Oncogene ProteinsLeukemia, Myeloid, AcuteDioxygenasesMicefms-Like Tyrosine Kinase 3

Keywords

Myeloid leukemiaCancer researchLoss of heterozygosityGeneLeukemiaMutationMolecular biologyBiologyImmunologyGeneticsAlleleMonocytesCytokinesHematologyEpigeneticsRDNA Methyltransferase 3ADioxygenasesDNA-Binding ProteinsLeukemia, Myeloid, AcuteMicefms-Like Tyrosine Kinase 3Proto-Oncogene ProteinsMedicineAnimalsHumansResearch Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being