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Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis

JCI Insight(2023)10.1172/jci.insight.168955Source: DataRank Database

Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis is a research paper published in JCI Insight (2023). On theSindex it has a DataRank of 0.907. It has been cited 22 times, with 15 citing works in its 1-hop citation network.

N/A

0.907DataRank · unranked

Scored on demand from live citation data

Open Access22 citations · 15 citing works in its network

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Linked data & code

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (18 grants)Impact (FWCI 3.81)OA: goldTopics (40)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 52%Citation Network 48%

Base Score Contribution

0.470

From this paper's citation signal

Citation Network Contribution

0.437

From 10 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 15 citers.

Effective treatment of recalcitrant Hailey-Hailey disease with dupilumab
JAAD Case Reports20245 citations10 referencesContributes 0.179
Grover disease shows type 2 immune activation and improves with dupilumab
British Journal of Dermatology20252 citations8 referencesContributes 0.137
Efficacy and safety of dupilumab in Hailey–Hailey disease: A multicentre cohort study
Journal of the European Academy of Dermatology and Venereology20251 citations10 referencesContributes 0.069
ATP2C1 knockdown induces abnormal expressions of cytoskeletal and tight junction proteins mimicking Hailey–Hailey disease
Indian Journal of Dermatology Venereology and Leprology20241 citations23 referencesContributes 0.030
Dupilumab for Hailey-Hailey disease
Journal of Dermatological Treatment20251 citations24 referencesContributes 0.029

Authors (13)

Hope E. Burks ORCID,Ziyou Ren ORCID,Jennifer L. Koetsier ORCID,Lam C. Tsoi ORCID,Paul W. Harms ORCID

Live enrichment

PubMed:37471166 PMC:PMC10543711 OpenAlex:https://openalex.org/W4384925058

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Grant: R01AR041836,R01AR043380,F32AR078645,P30AR075043,T32AR060710

Leo Foundation Grant

Grant: LF-OC-20-000585

National Cancer Institute

Grant: P30CA060553

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Grant: P30AR075049

NIAMS NIH HHS

Grant: P30 AR057216

NIAMS NIH HHS

Grant: P30 AR075043

NIAMS NIH HHS

Grant: R01 AR043380

NIAMS NIH HHS

Grant: R01 AR041836

NIGMS NIH HHS

Grant: R25 GM086262

NIAMS NIH HHS

Grant: T32 AR060710

NIAMS NIH HHS

Grant: F32 AR078645

National Institutes of Health

Grant: 5R01AR043380-12

Desmoplakin Assembly and Function in Epidermis

National Institutes of Health

Grant: 4T32AR060710-05

Post Graduate Program in Cutaneous Biology

National Institutes of Health

Grant: 1P30AR075049-01

Northwestern University Skin Biology and Diseases Resource-based Center

National Institutes of Health

Grant: 1F32AR078645-01A1

Mechanoregulation of the epidermal immune response: the role of desmoglein 1

National Institutes of Health

Grant: 5P30CA060553-12

The Robert H.Lurie Comprehensive Cancer Center

National Institutes of Health

Grant: 5R01AR041836-16

Function of Desmoglein 1/Pemphigus Foliaceus Antigen

National Institutes of Health

Grant: 5P30AR075043-04

University of Michigan Skin Biology and Diseases Resource-based Center

FWCI

3.81

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttp://insight.jci.org/articles/view/168955/files/pdf

GOLDhttp://insight.jci.org/articles/view/168955/files/pdf

publisherhttp://insight.jci.org/articles/view/168955/files/pdf

publisherhttps://insight.jci.org/articles/view/168955/files/pdf

journalhttps://doi.org/10.1172/jci.insight.168955

Fields of Study

Autoimmune Bullous Skin DiseasesGenetic and rare skin diseases.Dermatological and Skeletal DisordersBiologyMedicine0301 basic medicine0303 health sciences03 medical and health sciencesIchthyosisActinsHumansSkin DiseasesAcantholysisSkinGrover's disease

MeSH Terms

AcantholysisActinsHumansIchthyosisSkinSkin Diseases

Keywords

PathogenesisProfiling (computer programming)Computational biologyMedicineBioinformaticsBiologyComputer sciencePathologyCytoskeletonGenetic diseasesDermatologyAcantholysisTechnical AdvanceRIchthyosisHumansSkin DiseasesActinsSkin

Sustainable Development Goals

SDG 0: Good health and well-being