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Pyrimidine depletion enhances targeted and immune therapy combinations in acute myeloid leukemia

JCI Insight(2024)10.1172/jci.insight.173646Source: DataRank Database

Pyrimidine depletion enhances targeted and immune therapy combinations in acute myeloid leukemia is a research paper published in JCI Insight (2024). On theSindex it has a DataRank of 0. It has been cited 6 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access6 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 2.04)OA: goldTopics (56)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (33)

Sydney Fobare ORCID,Sandip Vibhute ORCID,Abeera Mehmood ORCID,Dennis C. Vroom,Mariah L. Johnson ORCID

Live enrichment

PubMed:38646934 OpenAlex:https://openalex.org/W4395037593

Paula and Rodger Riney Foundation

Grant: NA

National Cancer Institute

Grant: R35CA197734,P30CA016058,CA211404

National Institutes of Health

Grant: 3P30CA016058-15S1

CORE--HORMONE RECEPTOR LABORATORY

National Institutes of Health

Grant: 5R35CA197734-06

Targeted Therapy for Leukemia

National Institutes of Health

Grant: 5R50CA211404-04

Therapeutic insights through patient derived leukemia xenografts

NCI NIH HHS

Grant: P30 CA016058

NCI NIH HHS

Grant: R35 CA197734

NCI NIH HHS

Grant: R50 CA211404

FWCI

2.04

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttp://insight.jci.org/articles/view/173646/files/pdf

publisherhttp://insight.jci.org/articles/view/173646/files/pdf

publisherhttps://insight.jci.org/articles/view/173646/files/pdf

journalhttps://doi.org/10.1172/jci.insight.173646

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38646934

Fields of Study

Acute Myeloid Leukemia ResearchBiochemical and Molecular ResearchHematopoietic Stem Cell Transplantation0303 health sciences03 medical and health sciencesLeukemia, Myeloid, AcuteHumansPyrimidinesMiceAnimalsDihydroorotate DehydrogenaseImmunotherapyCell Line, TumorXenograft Model Antitumor AssaysFemale

MeSH Terms

Dihydroorotate DehydrogenaseAnimalsFemaleHumansImmunotherapyPyrimidinesLeukemia, Myeloid, AcuteXenograft Model Antitumor AssaysCell Line, TumorMice

Keywords

MedicineMyeloid leukemiaImmune systemMyeloidTolerabilityMyelopoiesisDihydroorotate dehydrogenaseImmunologyLeukemiaCancer researchPharmacologyOncologyInternal medicineAdverse effectBiologyHaematopoiesisStem cellLeukemia, Myeloid, AcuteMicePyrimidinesCell Line, TumorHumansAnimalsFemaleImmunotherapyXenograft Model Antitumor AssaysResearch ArticleCancer immunotherapyDrug therapyLeukemiasTherapeutics

Sustainable Development Goals

SDG 0: Good health and well-being