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The CLCA1/TMEM16A/Cl– current axis associates with H2S deficiency in diabetic kidney injury

JCI Insight(2025)10.1172/jci.insight.174848Source: DataRank Database

The CLCA1/TMEM16A/Cl– current axis associates with H2S deficiency in diabetic kidney injury is a research paper published in JCI Insight (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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Enrichment:Funding (27 grants)Impact (FWCI 0.77)OA: goldTopics (45)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Yuyang Sun ORCID,Falguni Das,Wenjun Ju ORCID,Viji Nair ORCID,Christopher G. Kevil ORCID

Live enrichment

PubMed:39782685 PMC:PMC11721299 OpenAlex:https://openalex.org/W4406166350

Department of Veterans Affairs Biomedical Laboratory Research and Development Service Merit Review Award

Grant: I01 BX001340,5I01 BX000926,1I01BX003234

Research Career Scientist Award

Grant: IK6BX005795

NIH

Grant: R01DE017102,R01DE022765

Institutional Development Award (IDeA) from NIGMS under

Grant: P20GM121307

George O’Brien Michigan Kidney Translational Core Center at University of Michigan, funded by NIH/NIDDK

Grant: 2P30-DK-081943

NIH

Grant: UH3DK114920,UO1DK114920,

NIH

Grant: U54DK137314-02

DOD

Grant: HT94252410202

BLRD VA

Grant: I01 BX003234

NIDDK NIH HHS

Grant: U01 DK114920

NIDDK NIH HHS

Grant: UH3 DK114920

BLRD VA

Grant: I01 BX000926

NIDDK NIH HHS

Grant: P30 DK081943

BLRD VA

Grant: I01 BX001340

NIDDK NIH HHS

Grant: P30 DK020572

NIDDK NIH HHS

Grant: U54 DK137314

NIDCR NIH HHS

Grant: R01 DE017102

NIDCR NIH HHS

Grant: R01 DE022765

NHLBI NIH HHS

Grant: R01 HL149264

National Institutes of Health

Grant: 3UH3DK114920-04S2

Nicotinamide Riboside for AKI in COVID-19 positive inpatients

National Institutes of Health

Grant: 5I01BX000926-12

Mechanisms of Renal Cell Injury

National Institutes of Health

Grant: 1IK6BX005795-01

BLRD Research Career Scientist Award Application

National Institutes of Health

Grant: 7I01BX003234-03

Mitochondrial-Derived Superoxide in Type 2 Diabetic Kidney Disease

National Institutes of Health

Grant: 5R01DE017102-03

TRPC1 and saliva secretion

National Institutes of Health

Grant: 5R01DE022765-04

Epigenetic regulations in Sjogern's syndrome

National Institutes of Health

Grant: 5P20GM121307-04

Center for Redox Biology and Cardiovascular Disease

National Institutes of Health

Grant: 2P30DK081943-06

Administrative Core

FWCI

0.77

Citation Percentile

0.7%

Citation Trend

2025

goldLicense: cc-by

journalhttps://doi.org/10.1172/jci.insight.174848

publisherhttps://doi.org/10.1172/jci.insight.174848

publisherhttps://insight.jci.org/articles/view/174848/files/pdf

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39782685

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11721299

Fields of Study

Ion channel regulation and functionNitric Oxide and Endothelin EffectsNeuroscience of respiration and sleep0303 health sciences03 medical and health sciences

MeSH Terms

Anoctamin-1Mechanistic Target of Rapamycin Complex 1AnimalsDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Diabetic NephropathiesHumansHydrogen SulfideKidney Tubules, ProximalMaleMice, Inbred C57BLNeoplasm ProteinsChloride ChannelsMice

Keywords

KidneyMedicineCurrent (fluid)Internal medicineEndocrinologyChemistryPhysicsExtracellular matrixDiabetesTherapeuticschloride channelsNephrologyMaleMechanistic Target of Rapamycin Complex 1Diabetes Mellitus, ExperimentalNeoplasm ProteinsKidney Tubules, ProximalMice, Inbred C57BLMiceDiabetes Mellitus, Type 2AnimalsHumansDiabetic NephropathiesHydrogen SulfideAnoctamin-1Research Article

Sustainable Development Goals

SDG 0: Good health and well-being

The CLCA1/TMEM16A/Cl– current axis associates with H2S deficiency in diabetic kidney injury

FAIR Checklist

Authors (14)

Funding (27 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)