Highly multiplexed imaging reveals prognostic immune and stromal spatial biomarkers in breast cancer is a dataset published in JCI Insight (2025). On theSindex it has a DataRank of 0.515, placing it in the top 37.5% of the data-sharing corpus. It has been cited 18 times, with 16 citing works in its 1-hop citation network. Its calibrated FAIR score is 29/100.
Ranks in the top 38% for downstream scientific impact
Linked data & code
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“https://www.synapse.org/#!Synapse:syn50134757/”— not found in the paper; verdict downgraded
The paper provides a web URL (Synapse link) rather than a persistent identifier from the recognized schemes (DOI, Handle, ARK, etc.). [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (4/5 passes agreed)]
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
The paper names Synapse as the repository holding the images and data files. [downgraded to 'partial' — no verifiable quote from the paper]
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
The dataset identifier (Synapse ID) appears only in the body text of the Data availability section, not as a reference-list entry. [downgraded to 'no' — no verifiable quote from the paper]
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
The data availability statement points to a repository (Synapse) with an accession, which is a repository record. [downgraded to 'partial' — no verifiable quote from the paper]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“The CycIF data were composed of 42 biomarkers imaged at a resolution of 0.325 μ m per pixel in entire cores with 1.2–1.4 mm diameters, with 1–2 full cores imaged per patient (Figure 1C).”
The dataset description is given in running prose, not as an itemised inventory (section, table, or enumerated list). [majority verdict 'partial' (3/5 passes agreed)]
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
The paper gives a direct link to Synapse with no stated precondition such as registration or embargo. [downgraded to 'partial' — no verifiable quote from the paper]
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
The paper provides a download URL but does not label the access level with any standard vocabulary term. [downgraded to 'no' — no verifiable quote from the paper]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
The data are from human subjects but the paper gives a direct download link with no gatekeeper named.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
No sentence states when the data become available or how long they persist.
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
The paper does not specify the file format of the released data. [majority verdict 'no' (4/5 passes agreed)]
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
No community standard for data or metadata is named in the paper.
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“https://doi.org/10.5281/zenodo.3518284”
The paper gives a DOI for the public IMC dataset used in the study. [majority verdict 'yes' (4/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
No licence is stated for the data; the article's CC BY 4.0 licence applies to the paper, not the data.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
No version token or date is given for the data snapshot. [majority verdict 'no' (4/5 passes agreed)]
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“https://github.com/engjen/cycIF_TMAs”
The paper provides a machine-resolvable code repository URL (GitHub) for the study's own code. [majority verdict 'yes' (4/5 passes agreed)]
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“NIH/NCI U54 CA209988”
An award/grant number is explicitly given, attached to a named funder. [majority verdict 'yes' (4/5 passes agreed)]
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“CycIF staining of tumor tissue was completed on JP-TMA1 and JP-TMA2 using our protocol: dx.doi.org/10.17504/protocols.io.23vggn6.”
The text names a specific protocol (with DOI) and software (Cellpose, Mesmer) used to produce the data. [majority verdict 'yes' (3/5 passes agreed)]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
“Supporting data values and antibody information is available in our Supporting Data Values file”
Variable definitions (antibody information) are provided inside the article (Supplementary Table 1), not as a separate file shipped with the data. [majority verdict 'partial' (4/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.442
From this paper's citation signal
Citation Network Contribution
0.0732
From 6 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 16 citers.
NIH/NCI
Grant: U54 CA209988,P30CA69533,P50 CA098131
OHSU Foundation
Grant: NA
Susan G. Komen
Grant: SAB210301
NCI NIH HHS
Grant: P50 CA098131
NIH HHS
Grant: S10 OD034224
NCI NIH HHS
Grant: P30 CA069533
NCI NIH HHS
Grant: U54 CA209988
National Institutes of Health
Grant: 3U54CA209988-03S1
Measuring, Modeling and Controlling Heterogeneity
National Institutes of Health
Grant: 3P30CA069533-21S3
OHSU Knight Cancer Institute
National Institutes of Health
Grant: 3P50CA098131-15S1
SPORE in Breast Cancer
FWCI
6.14
Citation Percentile
1.0%
Citation Trend
Fields of Study
MeSH Terms
Keywords
Sustainable Development Goals