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Oral octanoylcarnitine alleviates exercise intolerance in mouse models of long-chain fatty acid oxidation disorders

JCI Insight(2025)10.1172/jci.insight.199443Source: DataRank Database

Oral octanoylcarnitine alleviates exercise intolerance in mouse models of long-chain fatty acid oxidation disorders is a research paper published in JCI Insight (2025). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)Impact (FWCI 2.99)OA: goldTopics (47)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Yuxun Zhang ORCID,Sivakama S. Bharathi ORCID,Bob B. Zhang ORCID,Adam C. Richert ORCID,Alexandra V. Schmidt ORCID

Live enrichment

PubMed:41100184 PMC:PMC12643506 OpenAlex:https://openalex.org/W4415260368

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant: 5R01HD10360

national institute of health

Grant: DK090242

NIDDK NIH HHS

Grant: R01 DK090242

FWCI

2.99

Citation Percentile

0.9%

Citation Trend

2026

goldLicense: cc-by

journalhttp://insight.jci.org/articles/view/199443/files/pdf

publisherhttp://insight.jci.org/articles/view/199443/files/pdf

publisherhttps://insight.jci.org/articles/view/199443/files/pdf

journalhttps://doi.org/10.1172/jci.insight.199443

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41100184

Fields of Study

Adipose Tissue and MetabolismMuscle metabolism and nutritionMetabolomics and Mass Spectrometry StudiesAnimalsCarnitineMiceDisease Models, AnimalFatty AcidsOxidation-ReductionAdministration, OralMuscle, SkeletalLipid Metabolism, Inborn ErrorsMaleCarnitine O-AcetyltransferaseTriglyceridesExercise ToleranceMice, Inbred C57BLMyocardium

MeSH Terms

Administration, OralAnimalsCarnitineCarnitine O-AcetyltransferaseDisease Models, AnimalFatty AcidsLipid Metabolism, Inborn ErrorsMaleMice, Inbred C57BLMyocardiumOxidation-ReductionTriglyceridesExercise ToleranceMuscle, SkeletalMice

Keywords

Beta oxidationCarnitineSkeletal muscleBioenergeticsMitochondrionLactic acidosisLipid oxidationBioavailabilityMitochondrial myopathyExercise intoleranceGeneticsMetabolismTherapeuticsMonogenic Diseases

Oral octanoylcarnitine alleviates exercise intolerance in mouse models of long-chain fatty acid oxidation disorders

FAIR Checklist

Authors (10)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)