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Epigenetic modulator inhibition overcomes temozolomide chemoresistance and antagonizes tumor recurrence of glioblastoma

Journal of Clinical Investigation(2020)10.1172/jci127916Source: DataRank Database

Epigenetic modulator inhibition overcomes temozolomide chemoresistance and antagonizes tumor recurrence of glioblastoma is a research paper published in Journal of Clinical Investigation (2020). On theSindex it has a DataRank of 0.557. It has been cited 40 times.

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0.557DataRank · unranked

Scored on demand from live citation data

Open Access40 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 2.00)OA: bronzeTopics (51)Linked Datasets (12)DataCite Reuse (12)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.557

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (9)

Mingyang Cai ORCID,Grace Lee ORCID,Tong Zhao ORCID,Xiaofeng Song ORCID,Steven L. Giannotta ORCID

Live enrichment

PubMed:33016927 PMC:PMC7598052 OpenAlex:https://openalex.org/W3090910408

National Institutes of Health (NIH), California Institute of Regenerative Medicine

Grant: 5R01NS06721305,TG2-01161

Korea Research Institute of Chemical Technology

Grant: SI2031-50

NCI NIH HHS

Grant: DP2 CA206653

FWCI

2.00

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

bronze

journalhttp://www.jci.org/articles/view/127916/files/pdf

publisherhttp://www.jci.org/articles/view/127916/files/pdf

publisherhttps://www.jci.org/articles/view/127916/files/pdf

journalhttps://doi.org/10.1172/jci127916

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33016927

Fields of Study

Glioma Diagnosis and TreatmentEpigenetics and DNA MethylationHistone Deacetylase Inhibitors ResearchAnimalsBrain NeoplasmsCell Line, TumorDNA MethylationDNA, NeoplasmDrug Resistance, NeoplasmEpigenesis, GeneticGene Expression Regulation, NeoplasticGlioblastomaHumansMiceNeoplasm ProteinsTemozolomide

MeSH Terms

TemozolomideAnimalsBrain NeoplasmsDNA, NeoplasmGlioblastomaHumansNeoplasm ProteinsGene Expression Regulation, NeoplasticDrug Resistance, NeoplasmDNA MethylationEpigenesis, GeneticCell Line, TumorMice

Keywords

TemozolomideCancer researchUbiquitin ligaseEpigeneticsHistone deacetylaseBiologyMethyltransferaseDNA methylationTrichostatin AHistoneMdm2UbiquitinGliomaMethylationGeneticsApoptosisGeneGene expressionDrug therapyBrain cancerOncologyStem Cells

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 6 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.26661290figshare

Additional file 6 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.26661290.v1figshare

Additional file 5 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.26661287figshare

Additional file 4 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.26661284.v1figshare

Additional file 3 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.26661281.v1figshare

Additional file 2 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.24946745.v1figshare

Additional file 2 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.24946745figshare

Additional file 1 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.24946472figshare

Additional file 1 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.24946472.v1figshare

Additional file 5 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.26661287.v1figshare

Additional file 3 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.26661281figshare

Additional file 4 of MBD3 promotes epithelial-mesenchymal transition in gastric cancer cells by upregulating ACTG1 via the PI3K/AKT pathway

10.6084/m9.figshare.26661284figshare

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Epigenetic modulator inhibition overcomes temozolomide chemoresistance and antagonizes tumor recurrence of glioblastoma

FAIR Checklist

DataRank Breakdown

Authors (9)

Funding (3 grants)

Impact

Open Access

Topics

Linked Datasets (12)

Annotations (Europe PMC)

Related Papers (8)