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LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade

Journal of Clinical Investigation(2022)10.1172/jci154152Source: DataRank Database

LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade is a research paper published in Journal of Clinical Investigation (2022). On theSindex it has a DataRank of 0. It has been cited 44 times.

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Open Access44 citations

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Enrichment:Funding (6 grants)OA: goldTopics (27)IDs (PubMed, PMC)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (30)

Joost Koetsier,Trevin Kurtanich ORCID,Michael Engelbrecht Nielsen ORCID,Glenn Winn,Yunfei Wang ORCID

Live enrichment

PubMed:35552271 PMC:PMC9246385

NCI NIH HHS

Grant: P50 CA221703

NCI NIH HHS

Grant: R41 CA203456

NCI NIH HHS

Grant: P30 CA016672

National Institutes of Health

Grant: 1R41CA203456-01A1

Development of a small molecule activator of integrin cell adhesion to enhance therapeutic responses to checkpoint blockade in cancer

National Institutes of Health

Grant: 5P50CA221703-04

The University of Texas MD Anderson Cancer Center SPORE in Melanoma

National Institutes of Health

Grant: 3P30CA016672-41S4

Cancer Center Support (CORE) Grant

goldLicense: cc-by

publisherhttp://www.jci.org/articles/view/154152/files/pdf

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9246385

Europe_PMChttps://europepmc.org/articles/PMC9246385

Europe_PMChttps://europepmc.org/articles/PMC9246385?pdf=render

https://doi.org/10.1172/jci154152

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

T-LymphocytesCD8-Positive T-LymphocytesLymphocytes, Tumor-InfiltratingHumansMelanomaLymphocyte Function-Associated Antigen-1ImmunotherapyTumor MicroenvironmentCTLA-4 AntigenProgrammed Cell Death 1 Receptor

Keywords

TherapeuticsCancer ImmunotherapyT-LymphocytesProgrammed Cell Death 1 ReceptorRCD8-Positive T-LymphocytesLymphocyte Function-Associated Antigen-1Lymphocytes, Tumor-InfiltratingTumor MicroenvironmentMedicineHumansCTLA-4 AntigenImmunotherapyMelanomaResearch Article

Sustainable Development Goals

SDG 3: 3. Good health

LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade

FAIR Checklist

Authors (30)

Funding (6 grants)

Open Access

Topics

Annotations (Europe PMC)