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Surviving without BRCA2: MLH1 gets R-looped in to curtail genomic instability

Journal of Clinical Investigation(2024)10.1172/jci179325Source: DataRank Database

Surviving without BRCA2: MLH1 gets R-looped in to curtail genomic instability is a research paper published in Journal of Clinical Investigation (2024). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 0.32)OA: goldTopics (39)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (1)

Neil Johnson ORCID

Live enrichment

PubMed:38557488 PMC:PMC10977974 OpenAlex:https://openalex.org/W4393356640

NCI NIH HHS

Grant: R01 CA214799

National Institutes of Health

Grant: 5P30CA006927-49

Transgenic Mouse

National Institutes of Health

Grant: 3R01CA262466-02S1

Assessing DNA Polymerase Theta as a Therapeutic Target in BRCA1 Mutant Cancer

FWCI

0.32

Citation Percentile

0.5%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1172/jci179325

publisherhttps://doi.org/10.1172/jci179325

publisherhttps://www.jci.org/articles/view/179325/files/pdf

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38557488

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10977974

Fields of Study

DNA Repair MechanismsGenetic factors in colorectal cancerRNA Research and Splicing03 medical and health sciences0302 clinical medicineHumansAdaptor Proteins, Signal TransducingBRCA2 ProteinGenomic InstabilityMutL Protein Homolog 1MutS Homolog 2 ProteinNeoplasmsNuclear ProteinsBreast Neoplasms

MeSH Terms

MutL Protein Homolog 1Breast NeoplasmsHumansNeoplasmsNuclear ProteinsBRCA2 ProteinGenomic InstabilityAdaptor Proteins, Signal TransducingMutS Homolog 2 Protein

Keywords

MLH1Genome instabilityDNA mismatch repairBiologyLoss of heterozygosityCancer researchDNA repairMSH2Breast cancerGeneticsGeneCancerDNA damageDNAAlleleCommentary

Sustainable Development Goals

SDG 0: Climate action