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Transcriptome-guided GLP-1 receptor therapy rescues metabolic and behavioral disruptions in a Bardet-Biedl syndrome mouse model

Journal of Clinical Investigation(2025)10.1172/jci184636Source: DataRank Database

Transcriptome-guided GLP-1 receptor therapy rescues metabolic and behavioral disruptions in a Bardet-Biedl syndrome mouse model is a research paper published in Journal of Clinical Investigation (2025). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 7.51)OA: goldTopics (43)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Naila Haq ORCID,Mingxin Yang ORCID,Shelby Luckey,Samira Mansouri ORCID,Martha Campbell‐Thompson ORCID

Live enrichment

PubMed:40233116 PMC:PMC12165790 OpenAlex:https://openalex.org/W4409474390

NIDDK

Grant: DK116004,DK094871

American Heart Association

Grant: 23POST1026084

NIDDK NIH HHS

Grant: K99 DK094871

Biotechnology and Biological Sciences Research Council

Grant: BB/M020991/1

NIDDK NIH HHS

Grant: R01 DK116004

NIDDK NIH HHS

Grant: R00 DK094871

FWCI

7.51

Citation Percentile

1.0%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttp://www.jci.org/articles/view/184636/files/pdf

publisherhttp://www.jci.org/articles/view/184636/files/pdf

publisherhttps://www.jci.org/articles/view/184636/files/pdf

journalhttps://doi.org/10.1172/jci184636

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40233116

Fields of Study

Genetic and Kidney Cyst DiseasesGenetic Syndromes and ImprintingHedgehog Signaling Pathway StudiesAnimalsBardet-Biedl SyndromeMiceDisease Models, AnimalMice, KnockoutTranscriptomeGlucagon-Like Peptide-1 ReceptorHumansObesityMaleInsulinHyperphagia

MeSH Terms

Glucagon-Like Peptide-1 ReceptorAnimalsDisease Models, AnimalHumansHyperphagiaInsulinMaleObesityMice, KnockoutBardet-Biedl SyndromeMiceTranscriptome

Keywords

TranscriptomeBardet–Biedl syndromeMetabolic syndromeReceptorBiologyMedicineBioinformaticsEndocrinologyGeneticsPhenotypeGeneObesityGene expressionMetabolismMacrophagesMonogenic Diseases

Transcriptome-guided GLP-1 receptor therapy rescues metabolic and behavioral disruptions in a Bardet-Biedl syndrome mouse model

FAIR Checklist

Authors (9)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)