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Platelet-specific SLFN14 deletion causes macrothrombocytopenia and platelet dysfunction through dysregulated megakaryocyte and platelet gene expression

Journal of Clinical Investigation(2025)10.1172/jci189100Source: DataRank Database

Platelet-specific SLFN14 deletion causes macrothrombocytopenia and platelet dysfunction through dysregulated megakaryocyte and platelet gene expression is a research paper published in Journal of Clinical Investigation (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (11 grants)OA: goldTopics (14)IDs (PubMed, PMC)

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Authors (18)

Xenia Sawkulycz,Gabriel H. M. Araujo ORCID,Maximilian Englert ORCID,Lourdes Garcia‐Quintanilla ORCID,Sophie Smith ORCID

Live enrichment

PubMed:40794453 PMC:PMC12520693

British Heart Foundation

Grant: PG/16/103/32650,FS/18/11/33443,AA/18/2/34218

National Institutes of Health

Grant: GM097014,HL146544

Birmingham Biomedical Research Centre

Grant: NIHR203326

Deutsche Forschungsgemeinschaft

Grant: 519246588

British Heart Foundation

Grant: PG/24/11972

NHLBI NIH HHS

Grant: R01 HL146544

NIGMS NIH HHS

Grant: R01 GM097014

British Heart Foundation

Grant: FS/18/11/33443

British Heart Foundation

Grant: PG/16/103/32650

British Heart Foundation

Grant: AA/18/2/34218

British Heart Foundation

Grant: NH/18/3/33913

goldLicense: cc-by

publisherhttp://www.jci.org/articles/view/189100/files/pdf

publisherhttps://www.jci.org/articles/view/189100/files/pdf

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12520693

repositoryhttps://research.birmingham.ac.uk/en/publications/a2d08669-a52d-4db5-8f66-0c3a444d9465

Europe_PMChttps://europepmc.org/articles/PMC12520693

MeSH Terms

Blood PlateletsMegakaryocytesAnimalsMice, KnockoutHumansMiceThrombocytopeniaGene Expression RegulationGene Deletion

Keywords

GeneticsThrombinHematologyPlateletsMouse Models