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Impact of therapeutic inhibition of oncogenic cell signaling tyrosine kinase on cell metabolism: in vivo-detectable metabolic biomarkers of inhibition

Journal of Translational Medicine(2024)10.1186/s12967-024-05371-9Source: DataRank Database

Impact of therapeutic inhibition of oncogenic cell signaling tyrosine kinase on cell metabolism: in vivo-detectable metabolic biomarkers of inhibition is a research paper published in Journal of Translational Medicine (2024). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)Impact (FWCI 1.03)OA: goldTopics (59)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Pradeep Kumar Gupta ORCID,Johnvesly Basappa ORCID,Shengchun Wang ORCID,N. P. Sen,Cosimo Lobello ORCID

Live enrichment

PubMed:38965536 PMC:PMC11225145 OpenAlex:https://openalex.org/W4400319726

NIH

Grant: R01CA250102

NIH

Grant: R01CA228457

NIH

Grant: R01CA268601

NIH

Grant: R21CA280523

National Institutes of Health

Grant: 5R01CA268601-03

Metabolic Imaging of Targeted Therapies in Cancer

National Institutes of Health

Grant: 1R21CA280523-01A1

Translation of Noninvasive Metabolic Biomarkers to Targeted Therapy for Cancer

National Institutes of Health

Grant: 5R01CA250102-05

Melanoma: Metabolic Biomarkers of Response to Targeted Therapy

National Institutes of Health

Grant: 5R01CA228457-03

Metabolic Biomarkers of Response of Mantle Cell Lymphoma to Bruton Tyrosine Kinase Inhibition

FWCI

1.03

Citation Percentile

0.8%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1186/s12967-024-05371-9

publisherhttps://doi.org/10.1186/s12967-024-05371-9

publisherhttps://link.springer.com/content/pdf/10.1186/s12967-024-05371-9.pdf

publisherhttps://link.springer.com/article/10.1186/s12967-024-05371-9/fulltext.html

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38965536

Fields of Study

Advanced MRI Techniques and ApplicationsCancer, Hypoxia, and MetabolismMRI in cancer diagnosis0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Agammaglobulinaemia Tyrosine KinaseAnimalsHumansBiomarkers, TumorSignal TransductionBiomarkersLymphoma, Mantle-CellXenograft Model Antitumor AssaysCell Line, TumorProtein Kinase InhibitorsCell ProliferationMice

Keywords

GlycolysisBiochemistryPyruvate kinaseIn vivoPyrimidine metabolismPurine metabolismKinaseCholine kinaseMetabolismBiologyTyrosine kinaseTaurineBruton's tyrosine kinaseChemistryPurineSignal transductionAmino acidEnzymeBruton’s Tyrosine Kinase (Btk)Magnetic Resonance Spectroscopy (Mrs)Mantle Cell Lymphoma (Mcl)Proton Magnetic Resonance Spectroscopy (1H Mrs)Signaling InhibitionRna Sequence Analysis (Rna-seq)Ibrutinib (Ibr)Acp-196 (Acalabrutinib)Tricarboxylic Or Citric Acid Cycle (Tca)ResearchRLymphoma, Mantle-CellXenograft Model Antitumor AssaysMiceCell Line, TumorAgammaglobulinaemia Tyrosine KinaseBiomarkers, TumorMedicineHumansAnimalsProtein Kinase InhibitorsBiomarkersCell Proliferation

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Life below water

Impact of therapeutic inhibition of oncogenic cell signaling tyrosine kinase on cell metabolism: in vivo-detectable metabolic biomarkers of inhibition

FAIR Checklist

Authors (14)

Funding (8 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)