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Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation

Journal of Neuroinflammation(2020)10.1186/s12974-019-1644-8Source: DataRank Database

Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation is a research paper published in Journal of Neuroinflammation (2020). On theSindex it has a DataRank of 0. It has been cited 201 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access201 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 13.19)OA: goldTopics (41)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Mingming Zhu ORCID,Xiaohang Che ORCID,Huiyang Wang ORCID,Xing‐Jie Liang ORCID,Chunfu Wu ORCID

Live enrichment

PubMed:31926553 PMC:PMC6954631 OpenAlex:https://openalex.org/W3003308204

National Key Research and Development Program of China

Grant: 2018YFA0209800

National Natural Science Foundation of China

Grant: 81701829 and 31771031

FWCI

13.19

Citation Percentile

1.0%

Citation Trend

2018

2020

2021

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2026

goldLicense: cc-by

journalhttps://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-019-1644-8

publisherhttps://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-019-1644-8

journalhttps://doi.org/10.1186/s12974-019-1644-8

repositoryhttps://pubmed.ncbi.nlm.nih.gov/31926553

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/6954631

Fields of Study

Autophagy in Disease and TherapyNeuroinflammation and Neurodegeneration MechanismsAmyotrophic Lateral Sclerosis Research

MeSH Terms

AutophagosomesAnimalsAutophagyCell LineInflammationLipopolysaccharidesMaleMice, Inbred C57BLSignal TransductionDown-RegulationRats, Sprague-DawleyMicrogliaMiceRatsClass III Phosphatidylinositol 3-KinasesTOR Serine-Threonine Kinases

Keywords

NeuroinflammationAutophagyMicrogliaAutophagosomePI3K/AKT/mTOR pathwayCell biologyLipopolysaccharideLysosomeInflammationChemistryNeurodegenerationProinflammatory cytokineSignal transductionBiologyImmunologyApoptosisMedicineBiochemistryInternal medicineEnzymeMtorVps34

Sustainable Development Goals

SDG 0: Good health and well-being