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mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes

Journal of Neuroinflammation(2024)10.1186/s12974-024-03165-wSource: DataRank Database

mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes is a research paper published in Journal of Neuroinflammation (2024). On theSindex it has a DataRank of 0. It has been cited 17 times.

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Open Access17 citations

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Enrichment:Funding (18 grants)OA: goldTopics (39)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Brenda L. Rooney ORCID,Frank McCarthy ORCID,Wenlong Xia,Indigo V.L. Rose ORCID,Sophie Bax ORCID

Live enrichment

PubMed:39118084 PMC:PMC11312292

National Institutes of Health

Grant: F30 AG066418

National Institutes of Health

Grant: R01 AG062359

National Institutes of Health

Grant: R01NS097551

National Institutes of Health

Grant: T32 NS115706

National Institutes of Health

Grant: R01AG057342

Chan Zuckerberg Initiative

Grant: Early Career Acceleration Award

California Institute of Regenerative Medicine

Grant: EDUC4-12812

NINDS NIH HHS

Grant: R01 NS128021

NIGMS NIH HHS

Grant: T32 GM141323

NINDS NIH HHS

Grant: R21 NS133891

National Institutes of Health

Grant: 5R01AG057342-05

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National Institutes of Health

Grant: 5R21NS119954-02

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National Institutes of Health

Grant: 5P30AG062422-03

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National Institutes of Health

Grant: 1R01AG062359-01

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National Institutes of Health

Grant: 1T32NS115706-01

Predoctoral Training in Neurobiology

National Institutes of Health

Grant: 5R01NS097551-05

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National Institutes of Health

Grant: 5P01NS083513-07

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National Institutes of Health

Grant: 1F30AG066418-01

Elucidating cellular pathways controlling the reactive state of astrocytes in Alzheimer’s Disease

goldLicense: cc-by

publisherhttps://jneuroinflammation.biomedcentral.com/counter/pdf/10.1186/s12974-024-03165-w

publisherhttps://link.springer.com/content/pdf/10.1186/s12974-024-03165-w.pdf

publisherhttps://link.springer.com/article/10.1186/s12974-024-03165-w/fulltext.html

repositoryhttps://escholarship.org/content/qt1vr1g65f/qt1vr1g65f.pdf?t=sigif6

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11312292/pdf/12974_2024_Article_3165.pdf

Fields of Study

MedicineBiology0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

AstrocytesCells, CulturedEndosomesLysosomesHumansInflammationInterleukinsExosomesInduced Pluripotent Stem CellsTOR Serine-Threonine KinasesNeuroinflammatory Diseases

Keywords

AstrocytesneuroinflammationMtorExtracellular VesiclesIl-32Endolysosomal SystemInflammatory Reactive Astrocytes570CellsInduced Pluripotent Stem CellsEndosomesExosomesHumansRC346-429Cells, CulturedInflammationCulturedResearchTOR Serine-Threonine KinasesInterleukinsNeuroinflammatory DiseasesNeurology. Diseases of the nervous systemLysosomes

Sustainable Development Goals

SDG 3: 3. Good health

mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes

FAIR Checklist

Authors (14)

Funding (18 grants)

Open Access

Topics

Annotations (Europe PMC)