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Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

Molecular Neurodegeneration(2024)10.1186/s13024-024-00738-4Source: DataRank Database

Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation is a research paper published in Molecular Neurodegeneration (2024). On theSindex it has a DataRank of 0.449. It has been cited 19 times.

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0.449DataRank · unranked

Scored on demand from live citation data

Open Access19 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (16 grants)OA: goldTopics (42)IDs (PubMed, PMC)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.449

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (16)

Huizhong Li ORCID,Kashyap Sreeram,Tuyana Malankhanova ORCID,Ravindra Boddu,Samuel Strader ORCID

Live enrichment

PubMed:38862989 PMC:PMC11167795

National Institute of Neurological Disorders and Stroke

Grant: R01 NS064934

National Institute of Neurological Disorders and Stroke

Grant: P50 NS108678

National Institute of Neurological Disorders and Stroke

Grant: R01 NS119528

National Institute of Neurological Disorders and Stroke

Grant: R01 NS105432

Michael J. Fox Foundation for Parkinson’s Research

Grant: Michael J. Fox Foundation for Parkinson’s Research

Michael J. Fox Foundation for Parkinson's Research

Grant: Michael J. Fox Foundation for Parkinson's Research

National Institutes of Health

Grant: 1RF1NS115767-01A1

Role of Rab27b in synucleinopathies

National Institutes of Health

Grant: 5R01NS064934-11

Mechanisms of LRRK2 Mediated Neurotoxicity

National Institutes of Health

Grant: 3R01NS119528-04S2

Mechanisms of mitochondrial genome integrity in familial and idiopathic Parkinson's disease

National Institutes of Health

Grant: 5P30DK034987-28

Administrative Core and Enrichment Program

National Institutes of Health

Grant: 5R01NS105432-02

Mechanisms of VPS35-Dependent Neurodegeneration in Parkinson's Disease

National Institutes of Health

Grant: 5T32GM008361-26

Medical Scientist Training Program

National Institutes of Health

Grant: 5R13GM109532-06

Southeastern Medical Scientist Symposium

National Institutes of Health

Grant: 5U01NS104326-05

Clinical Trial Readiness for SCA1 and SCA3

National Institutes of Health

Grant: 5R01NS112203-05

14-3-3 phosphorylation in Parkinson's disease

National Institutes of Health

Grant: 5P50NS108675-02

Innate and Adaptive Immunity in Parkinson Disease

goldLicense: CC BY

publisherhttps://link.springer.com/content/pdf/10.1186/s13024-024-00738-4.pdf

publisherhttps://link.springer.com/article/10.1186/s13024-024-00738-4/fulltext.html

Europe_PMChttps://europepmc.org/articles/PMC11167795

Europe_PMChttps://europepmc.org/articles/PMC11167795?pdf=render

https://doi.org/10.1186/s13024-024-00738-4

Fields of Study

0301 basic medicine03 medical and health sciences0302 clinical medicine

MeSH Terms

AnimalsMice, TransgenicHumansMiceRatsParkinson DiseaseInflammationrab GTP-Binding ProteinsSeverity of Illness IndexPhosphorylationAgedMiddle AgedFemaleMaleLeucine-Rich Repeat Serine-Threonine Protein Kinase-2

Keywords

InflammationNeurodegenerationBlood-based BiomarkersTranscriptomic AnalysisSingle-molecule Array AssaysMaleMice, TransgenicLeucine-Rich Repeat Serine-Threonine Protein Kinase-2Severity of Illness IndexMiceAnimalsHumansPhosphorylationRC346-429AgedRC952-954.6Parkinson DiseaseMiddle AgedRatsGeriatricsrab GTP-Binding ProteinsFemaleNeurology. Diseases of the nervous systemResearch Article

Sustainable Development Goals

SDG 3: 3. Good health