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Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

Genome biology(2021)10.1186/s13059-021-02275-5Source: DataRank Database

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders is a research paper published in Genome biology (2021). On theSindex it has a DataRank of 2.0. It has been cited 108 times, with 76 citing works in its 1-hop citation network.

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2.0DataRank · unranked

Scored on demand from live citation data

Open Access108 citations · 76 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (21 grants)Impact (FWCI 4.57)OA: goldTopics (32)Linked Datasets (25)DataCite Reuse (25)IDs (PubMed, PMC, OpenAlex)Annotations (4)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 36%Citation Network 64%

Base Score Contribution

0.704

From this paper's citation signal

Citation Network Contribution

1.3

From 58 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 76 citers.

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Critical evaluation of the reliability of DNA methylation probes on the Illumina MethylationEPIC v1.0 BeadChip microarrays
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The Involvement of RAGE and Its Ligands during Progression of ALS in SOD1 G93A Transgenic Mice
International Journal of Molecular Sciences202218 citations47 referencesContributes 0.063
A DNA methylation signature in the stress driver gene Fkbp5 indicates a neuropathic component in chronic pain
Clinical Epigenetics202316 citations49 referencesContributes 0.058
Identification of COVID-19-Associated DNA Methylation Variations by Integrating Methylation Array and scRNA-Seq Data at Cell-Type Resolution
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Authors (72)

Marta F. Nabais ORCID,the Alzheimer’s Disease Neuroimaging Initiative,Simon M. Laws ORCID,Tian Lin ORCID,Costanza L. Vallerga ORCID

Live enrichment

PubMed:33771206 PMC:PMC8004462 OpenAlex:https://openalex.org/W3137908860

Wellcome Trust

Grant: 108890/Z/15/Z

NIA NIH HHS

Grant: U01 AG016976

ZonMw

Grant: 733051071

Economic and Social Research Council

Grant: ES/L008238/1

Health Research Board

Grant: JPI-JPND-2017-1

NIA NIH HHS

Grant: R01 AG033193

Wellcome Trust

Grant: 082604

Motor Neurone Disease Association

Grant: TURNER/OCT15/972-797

National Institute for Health Research (NIHR)

Grant: NIHR202421

NIA NIH HHS

Grant: U01 AG024904

NIA NIH HHS

Grant: U01 AG032984

Wellcome Trust

Grant: 082604/2/07/Z

Medical Research Council

Grant: 503480

Medical Research Council

Grant: MR/R024804/1

National Institute for Health Research (NIHR)

Grant: NF-SI-0617-10077

NHLBI NIH HHS

Grant: R01 HL105756

Medical Research Council

Grant: UKDRI-6001

NIA NIH HHS

Grant: U24 AG021886

European Commission

Grant: 633413

Efficacy and safety of low-dose IL-2 (ld-IL-2) as a Treg enhancer for anti-neuroinflammatory therapy in newly diagnosed Amyotrophic Lateral Sclerosis (ALS) patients

National Institute for Health Research (NIHR)

Wellcome Trust

FWCI

4.57

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://genomebiology.biomedcentral.com/counter/pdf/10.1186/s13059-021-02275-5

publisherhttps://genomebiology.biomedcentral.com/counter/pdf/10.1186/s13059-021-02275-5

journalhttps://doi.org/10.1186/s13059-021-02275-5

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33771206

repositoryhttps://kclpure.kcl.ac.uk/portal/en/publications/fe55cdee-3ad6-4719-8fae-6f668f795ed3

Fields of Study

Amyotrophic Lateral Sclerosis ResearchEpigenetics and DNA MethylationNeuroinflammation and Neurodegeneration Mechanisms

MeSH Terms

AllelesBlood CellsDisease SusceptibilityHumansBiomarkersCase-Control StudiesDNA MethylationNeurodegenerative DiseasesGenetic Predisposition to DiseaseGene Expression ProfilingEpigenesis, GeneticGenome-Wide Association StudyGenetic Loci

Keywords

BiologyHuman geneticsDNA methylationGeneticsGenome BiologyComputational biologyGenomeGenomicsEvolutionary biologyGeneGene expressionNeurodegenerative DisordersInflammatory MarkersMixed-linear ModelsMethylation Profile ScoreOut-of-sample Classification

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 1 of Distinct sex-specific DNA methylation differences in Alzheimer’s disease

10.6084/m9.figshare.21129953.v1figshare

Additional file 1 of Distinct sex-specific DNA methylation differences in Alzheimer’s disease

10.6084/m9.figshare.21129953figshare

Additional file 2 of A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples

10.6084/m9.figshare.21456173.v1figshare

Additional file 2 of A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples

10.6084/m9.figshare.21456173figshare

Additional file 1 of Systemic interindividual epigenetic variation in humans is associated with transposable elements and under strong genetic control

10.6084/m9.figshare.22610218.v1figshare

Additional file 1 of Systemic interindividual epigenetic variation in humans is associated with transposable elements and under strong genetic control

10.6084/m9.figshare.22610218figshare

Additional file 6 of A novel approach toward optimal workflow selection for DNA methylation biomarker discovery

10.6084/m9.figshare.26671305.v1figshare

Additional file 6 of A novel approach toward optimal workflow selection for DNA methylation biomarker discovery

10.6084/m9.figshare.26671305figshare

Additional file 1 of An EWAS of dementia biomarkers and their associations with age, African ancestry, and PTSD

10.6084/m9.figshare.26687882.v1figshare

Additional file 1 of An EWAS of dementia biomarkers and their associations with age, African ancestry, and PTSD

10.6084/m9.figshare.26687882figshare

Additional file 3 of An EWAS of dementia biomarkers and their associations with age, African ancestry, and PTSD

10.6084/m9.figshare.26687888.v1figshare

Additional file 3 of An EWAS of dementia biomarkers and their associations with age, African ancestry, and PTSD

10.6084/m9.figshare.26687888figshare

Additional file 2 of An EWAS of dementia biomarkers and their associations with age, African ancestry, and PTSD

10.6084/m9.figshare.26687885figshare

Additional file 2 of An EWAS of dementia biomarkers and their associations with age, African ancestry, and PTSD

10.6084/m9.figshare.26687885.v1figshare

Additional file 4 of A novel approach toward optimal workflow selection for DNA methylation biomarker discovery

10.6084/m9.figshare.26671299figshare

Additional file 5 of A novel approach toward optimal workflow selection for DNA methylation biomarker discovery

10.6084/m9.figshare.26671302figshare

Additional file 5 of A novel approach toward optimal workflow selection for DNA methylation biomarker discovery

10.6084/m9.figshare.26671302.v1figshare

Additional file 4 of A novel approach toward optimal workflow selection for DNA methylation biomarker discovery

10.6084/m9.figshare.26671299.v1figshare

Additional file 2 of A novel approach toward optimal workflow selection for DNA methylation biomarker discovery

10.6084/m9.figshare.26671293.v1figshare

Additional file 2 of A novel approach toward optimal workflow selection for DNA methylation biomarker discovery

10.6084/m9.figshare.26671293figshare

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Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (72)

Funding (21 grants)

Impact

Open Access

Topics

Linked Datasets (25)

Annotations (Europe PMC)

Related Papers (10)