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Distinct signatures of codon and codon pair usage in 32 primary tumor types in the novel database CancerCoCoPUTs for cancer-specific codon usage

Genome Medicine(2021)10.1186/s13073-021-00935-6Source: DataRank Database

Distinct signatures of codon and codon pair usage in 32 primary tumor types in the novel database CancerCoCoPUTs for cancer-specific codon usage is a research paper published in Genome Medicine (2021). On theSindex it has a DataRank of 0. It has been cited 29 times.

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Open Access29 citations

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Enrichment:Funding (4 grants)Impact (FWCI 1.63)OA: goldTopics (54)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

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Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Jacob Kames ORCID,Haim Bar ORCID,Anton A. Komar ORCID,Aikaterini Alexaki ORCID,Juan C. Ibla ORCID

Live enrichment

PubMed:34321100 PMC:PMC8317675 OpenAlex:https://openalex.org/W3183518827

National Institutes of Health

Grant: HL151392

NHLBI NIH HHS

Grant: R01 HL151392

National Institutes of Health

Grant: 1R01HL151392-01

Safer and more effective FIX therapeutics: impact of codon optimization

U.S. Food and Drug Administration

FWCI

1.63

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://genomemedicine.biomedcentral.com/counter/pdf/10.1186/s13073-021-00935-6

publisherhttps://genomemedicine.biomedcentral.com/counter/pdf/10.1186/s13073-021-00935-6

publisherhttps://link.springer.com/content/pdf/10.1186/s13073-021-00935-6.pdf

publisherhttps://link.springer.com/article/10.1186/s13073-021-00935-6/fulltext.html

journalhttps://doi.org/10.1186/s13073-021-00935-6

Fields of Study

RNA and protein synthesis mechanismsRNA modifications and cancerGenomics and Phylogenetic Studies0301 basic medicine03 medical and health sciences

MeSH Terms

Codon UsageCodonHumansNeoplasmsPrognosisBiomarkers, TumorGene Expression Regulation, NeoplasticComputational BiologyGene Expression ProfilingGenomicsDatabases, GeneticKaplan-Meier EstimateGenome-Wide Association StudyTranscriptome

Keywords

Codon usage biasTranscriptomeBiologyCancerGeneComputational biologyGeneticsGenomeBioinformaticsGene expressionCodon usageSurvival analysisSynonymous codonsInvasive Ductal CarcinomaInvasive Lobular CarcinomaThe Cancer Genome Atlas (Tcga)Relative Synonymous Codon Usage (Rscu)Cancer TranscriptomeCodon PairCancercocoputsKaplan-Meier EstimateQH426-470NeoplasmsDatabases, GeneticBiomarkers, TumorHumansCodonResearchGene Expression ProfilingRGenomicsPrognosisGene Expression Regulation, NeoplasticMedicineGenome-Wide Association Study

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Distinct signatures of codon and codon pair usage in 32 primary tumor types in the novel database CancerCoCoPUTs for cancer-specific codon usage

FAIR Checklist

Authors (11)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)