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Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01237-zSource: DataRank Database

Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates is a research paper published in Acta Neuropathologica Communications (2021). On theSindex it has a DataRank of 0. It has been cited 15 times.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 2.84)OA: goldTopics (78)Linked Datasets (20)DataCite Reuse (20)IDs (PubMed, PMC, OpenAlex)SDGs (2)

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Context only (not used in score)

Findable (2/2)

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Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (10)

Donna Klinedinst ORCID,Fabian‐Xosé Fernandez ORCID,Bei Cheng ORCID,Alena Savonenko ORCID,Benjamin Devenney ORCID

Live enrichment

PubMed:34399854 PMC:PMC8365939 OpenAlex:https://openalex.org/W3193734927

national institutes of health

Grant: R01HD038384

national institutes of health

Grant: R21HD098540

NIA NIH HHS

Grant: P30 AG066507

National Institutes of Health

Grant: 3R01HD038384-10S1

Genomic Approaches to Aneuploidy

National Institutes of Health

Grant: 5R21HD098540-02

Chromosome 21 Elimination In A New Mouse Model of Down Syndrome

FWCI

2.84

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://actaneurocomms.biomedcentral.com/track/pdf/10.1186/s40478-021-01237-z

publisherhttps://actaneurocomms.biomedcentral.com/track/pdf/10.1186/s40478-021-01237-z

publisherhttps://link.springer.com/content/pdf/10.1186/s40478-021-01237-z.pdf

publisherhttps://link.springer.com/article/10.1186/s40478-021-01237-z/fulltext.html

journalhttps://doi.org/10.1186/s40478-021-01237-z

Fields of Study

Down syndrome and intellectual disability researchNeurogenesis and neuroplasticity mechanismsAlzheimer's disease research and treatments0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsCerebellumCognitionDisease Models, AnimalDown SyndromeGene Knock-In TechniquesHedgehog ProteinsHippocampusHumansLearningLocomotionMemoryMiceMice, TransgenicProsencephalonSpatial ProcessingZinc Finger Protein GLI1

MeSH Terms

Zinc Finger Protein GLI1AnimalsCerebellumCognitionDisease Models, AnimalDown SyndromeHippocampusHumansLearningLocomotionMemoryMice, TransgenicProsencephalonMiceHedgehog ProteinsGene Knock-In TechniquesSpatial Processing

Keywords

ForebrainCognitionNeurologyPloidyNeuroscienceFunction (biology)BiologyMedicinePathologyPsychologyCell biologyGeneticsGeneCentral nervous systemSonic hedgehogCognitive functionDown syndromeHyperactivityTs65dnTre-hshhMice, TransgenicHippocampusZinc Finger Protein GLI1MiceProsencephalonSpatial ProcessingMemoryCerebellumAnimalsHumansLearningHedgehog ProteinsGene Knock-In TechniquesRC346-429ResearchDisease Models, AnimalNeurology. Diseases of the nervous systemLocomotion

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Quality Education

Additional file 11 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 11 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 4 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 4 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 1 of Loss of GDE2 leads to complex behavioral changes including memory impairment

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Additional file 1 of Loss of GDE2 leads to complex behavioral changes including memory impairment

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Additional file 2 of Loss of GDE2 leads to complex behavioral changes including memory impairment

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Additional file 2 of Loss of GDE2 leads to complex behavioral changes including memory impairment

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Additional file 6 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 6 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 5 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 10 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 5 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 10 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 7 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 9 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 9 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 8 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

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Additional file 8 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

10.6084/m9.figshare.15179453figshare

Additional file 7 of Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

10.6084/m9.figshare.15179450.v1figshare