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The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

Acta Neuropathologica Communications(2022)10.1186/s40478-021-01285-5Source: DataRank Database

The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects is a research paper published in Acta Neuropathologica Communications (2022). On theSindex it has a DataRank of 0. It has been cited 67 times.

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Open Access67 citations

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Enrichment:Funding (13 grants)Impact (FWCI 7.06)OA: goldTopics (45)Linked Datasets (25)DataCite Reuse (25)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

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Context only (not used in score)

Findable (2/2)

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Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (22)

Orthis Saha ORCID,Bruna Soares Landeira ORCID,Ana Raquel Melo de Farias ORCID,Xavier Hermant,Arnaud Carrier

Live enrichment

PubMed:34998435 PMC:PMC8742943 OpenAlex:https://openalex.org/W4220665319

european regional development fund and hauts de france regional council

Grant: 18006176

metropole européenne de lille

Grant: contract_2016_ESR_05

french state

Grant: 2018-3-CTRL_IPL_Phase2

french state

Grant: Labex Distalz

agence nationale de la recherche

Grant: ANR-10-LABX-46

agence nationale de la recherche

Grant: ANR-10-EQPX-07-01

association france alzheimer

Grant: #328 ADhesion

association france alzheimer

Grant: #1999 BIN1DROSO

fondation vaincre alzheimer

Grant: #13755

fondation pour la recherche médicale

Grant: ALZ201912009628

fondation pour la recherche médicale

Grant: ALZ201906008477

NIH HHS

Grant: P40 OD010949

NIH HHS

Grant: P40 OD018537

FWCI

7.06

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-021-01285-5

publisherhttps://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-021-01285-5

publisherhttps://link.springer.com/content/pdf/10.1186/s40478-021-01285-5.pdf

publisherhttps://link.springer.com/article/10.1186/s40478-021-01285-5/fulltext.html

journalhttps://doi.org/10.1186/s40478-021-01285-5

Fields of Study

Alzheimer's disease research and treatmentsCellular transport and secretionCholinesterase and Neurodegenerative DiseasesAlzheimer DiseaseAnimalsAnimals, Genetically ModifiedBrainDrosophila ProteinsDrosophila melanogasterEndosomesHumansInduced Pluripotent Stem CellsNerve DegenerationNeuronsTranscription Factors

MeSH Terms

Alzheimer DiseaseAnimalsBrainDrosophila melanogasterHumansNerve DegenerationNeuronsEndosomesTranscription FactorsDrosophila ProteinsAnimals, Genetically ModifiedInduced Pluripotent Stem Cells

Keywords

EndosomeNeurodegenerationBiologyCell biologyGene isoformAlzheimer's diseaseNeuroscienceGeneGeneticsMedicineDiseasePathologyIntracellularDrosophilaAlzheimer’s diseaseEarly EndosomeBin1 IsoformsHuman Induced Neurons

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 11 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 11 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 1 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 1 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 2 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 2 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 3 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 3 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 4 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 4 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 5 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 5 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 6 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 6 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 7 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 7 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 8 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 8 of The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Additional file 1 of Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer’s disease brains

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Additional file 1 of Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer’s disease brains

10.6084/m9.figshare.26622151figshare

The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

FAIR Checklist

Authors (22)

Funding (13 grants)

Impact

Open Access

Topics

Linked Datasets (25)

Annotations (Europe PMC)