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Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01288-2Source: DataRank Database

Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro is a research paper published in Acta Neuropathologica Communications (2021). On theSindex it has a DataRank of 0. It has been cited 82 times.

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Open Access82 citations

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Enrichment:Funding (4 grants)Impact (FWCI 4.77)OA: goldTopics (39)Linked Datasets (16)DataCite Reuse (16)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (9)

Jahan Ara ORCID,Norihito Uemura ORCID,Marshall G. Lougee ORCID,Emily S. Meymand ORCID,Bin Zhang ORCID

Live enrichment

PubMed:34819159 OpenAlex:https://openalex.org/W3216350529

National Institute on Aging

Grant: U19-AG062418

National Institute on Aging

Grant: T32-AG000255

National Institute of Neurological Disorders and Stroke

Grant: R01-NS103873

National Institute of Neurological Disorders and Stroke

Grant: U19-NS110456

FWCI

4.77

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-021-01288-2

publisherhttps://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-021-01288-2

publisherhttps://link.springer.com/content/pdf/10.1186/s40478-021-01288-2.pdf

publisherhttps://link.springer.com/article/10.1186/s40478-021-01288-2/fulltext.html

journalhttps://doi.org/10.1186/s40478-021-01288-2

Fields of Study

Parkinson's Disease Mechanisms and TreatmentsBotulinum Toxin and Related Neurological DisordersAlzheimer's disease research and treatments

MeSH Terms

AnimalsAutopsyBrain ChemistryFemaleFluorescent DyesHumansImmunohistochemistryMice, Inbred C3HMice, Inbred C57BLProtein ConformationLewy BodiesMicealpha-SynucleinPrimary Cell Culture

Keywords

FibrilIn vitroProtein aggregationSynucleinopathiesRecombinant DNAAlpha-synucleinInclusion bodiesCell biologyAmyloid (mycology)IntracellularBiologyChemistryPhenotypeLewy bodyCytoplasmic inclusionBiophysicsParkinson's diseasePathologyBiochemistryCytoplasmMedicineDisease

Sustainable Development Goals

SDG 0: Life in Land

Additional file 7 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 3 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 8 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 8 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 5 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 7 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 3 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 1 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 5 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 4 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 6 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 6 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 2 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 1 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 2 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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Additional file 4 of Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro

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