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Differential gene regulation in DAPT-treated Hydra reveals candidate direct Notch signalling targets

Journal of Cell Science(2021)10.1242/jcs.258768Source: DataRank Database

Differential gene regulation in DAPT-treated Hydra reveals candidate direct Notch signalling targets is a research paper published in Journal of Cell Science (2021). On theSindex it has a DataRank of 0.558. It has been cited 15 times, with 11 citing works in its 1-hop citation network.

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0.558DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access15 citations · 11 citing works in its network
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›Methodology & internals
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring
Enrichment:Funding (2 grants)Topics (12)IDs (PubMed, PMC)Annotations (3)

FAIR Checklist

Context only (not used in score)
Findable (1/2)
  • Has DOI
Accessible (1/2)
  • Open Access
Interoperable (0/2)
    Reusable (0/3)

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      DataRank Breakdown

      Base Score 75%Citation Network 25%

      Base Score Contribution

      0.416

      From this paper's citation signal

      Citation Network Contribution

      0.142

      From 6 citing papers with measurable signal

      Learn more about DataRank methodology →

      Top 5 citers driving the network score

      Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 11 citers.

      1. Cysteine and glycine-rich protein 2 is crucial for maintaining the malignant phenotypes of gliomas through its action on Notch signalling cascade
        Toxicology and Applied Pharmacology20247 citations37 referencesContributes 0.056
      2. H4K20me1 plays a dual role in transcriptional regulation of regeneration and axis patterning inHydra
        Life Science Alliance20236 citations48 referencesContributes 0.041
      3. Unexpected Distribution of Chitin and Chitin Synthase across Soft-Bodied Cnidarians
        Biomolecules202313 citations88 referencesContributes 0.030
      4. The Notch pathway in Metazoa: a comparative analysis across cnidarians and beyond
        EvoDevo20252 citations60 referencesContributes 0.018
      5. The Hydra stem cell system – Revisited
        Cells and Development202334 citations282 referencesContributes 0.013

      Authors (8)

      Stefan SiebertORCID,Stefan KrebsORCID,Jack F. CazetORCID,Andrea Prexl,Qin Pan
      Live enrichment
      PubMed:34346482PMC:PMC8353520

      Deutsche Forschungsgemeinschaft

      Grant: BO1748-12-1

      National Institutes of Health

      Grant: R35GM133689

      MeSH Terms

      AnimalsHydraPlatelet Aggregation InhibitorsSignal TransductionCell DifferentiationGene Expression RegulationReceptors, Notch

      Keywords

      HydraWnt pathwayNotch PathwayAxis FormationNematocyte Differentiation