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Leveraging biochemical reactions to unravel functional impacts of cancer somatic variants affecting protein interaction interfaces

F1000Research(2022)10.12688/f1000research.74395.2Source: DataRank Database

Leveraging biochemical reactions to unravel functional impacts of cancer somatic variants affecting protein interaction interfaces is a research paper published in F1000Research (2022). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)OA: goldTopics (21)IDs (PubMed)SDGs (1)

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Authors (5)

Joshua Burkhart ORCID,Matthew J. Betts ORCID,Robert B. Russell ORCID,Guanming Wu ORCID,Francesco Raimondi ORCID

Live enrichment

PubMed:19162232

National Human Genome Research Institute

Grant: AwardNumberU41HG003751(GW)

U.S. National Library of Medicine

Grant: 5T15LM007088-29(JGB)

Associazione Italiana per la Ricerca sul Cancro

Grant: (MFAG2020-ID.24317)

Alexander von Humboldt-Stiftung

Grant: post-doctoralfellowship

Italian Ministry of University and Research

Grant: MFAG 2020 - ID. 24317

Germany Research Foundation

Grant: Cell Networks Excellence initiative

National Institutes of Health

Grant: 5U41HG003751-07

Reactome: An Open Knowledgebase of Human Pathways

National Institutes of Health

Grant: 5T15LM007088-29

Research Training in Biomedical Informatics and Data Science at Oregon Health & Science University

goldLicense: cc-by

publisherhttps://doi.org/10.12688/f1000research.74395.2

publisherhttps://f1000research.com/articles/10-1111/v2/xml

publisherhttps://f1000research.com/articles/10-1111/v2/pdf

publisherhttps://f1000research.com/articles/10-1111/v2/iparadigms

https://doi.org/10.12688/f1000research.74395.1

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Proteomicsvariant interpretationReactomeProteinscancer mutationstructural bioinformaticsnetwork bioinformaticsbiochemical reactionNeoplasmsMutationStructural bioinformatics, network bioinformatics, biological process, variant interpretation, biochemical reactions, PPI network, biological pathways, cancer mutations, ReactomeHumansprotein-protein interaction networkbiological processPPI network; Reactome; Structural bioinformatics; biochemical reactions; biological pathways; biological process; cancer mutations; network bioinformatics; variant interpretationResearch ArticleSignal Transductionbiological pathway

Sustainable Development Goals

SDG 3: 3. Good health