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Yap suppresses T-cell function and infiltration in the tumor microenvironment

PLoS Biology(2020)10.1371/journal.pbio.3000591Source: DataRank Database

Yap suppresses T-cell function and infiltration in the tumor microenvironment is a research paper published in PLoS Biology (2020). On theSindex it has a DataRank of 0. It has been cited 110 times.

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Open Access110 citations

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Enrichment:Funding (7 grants)Impact (FWCI 8.09)OA: goldTopics (74)Linked Datasets (25)DataCite Reuse (25)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

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Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (7)

Nan Cheng,Anthony Federico ORCID,Emily M. Slaby ORCID,Stefano Monti ORCID,Gregory L. Szeto ORCID

Live enrichment

PubMed:31929526 PMC:PMC6980695 OpenAlex:https://openalex.org/W3000155410

National Heart, Lung, and Blood Institute

Grant: R01HL124392

National Cancer Institute

Grant: P30CA134274

National Cancer Institute

Grant: R25CA186872

American Cancer Society

Grant: RSG-17-138-01-CSM

National Institutes of Health

Grant: 5R01HL124392-04

Defining epithelial cell polarity cues that direct cell fate

National Institutes of Health

Grant: 2P30CA134274-04

Protocol Specific Research

National Institutes of Health

Grant: 5R25CA186872-05

The Nathan Schnaper Intern Program in Translational Cancer Research

FWCI

8.09

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1371/journal.pbio.3000591

publisherhttps://doi.org/10.1371/journal.pbio.3000591

publisherhttps://dx.plos.org/10.1371/journal.pbio.3000591

repositoryhttps://pubmed.ncbi.nlm.nih.gov/31929526

repositoryhttps://doaj.org/article/68482584129348898ba9324233f6715f

Fields of Study

Hippo pathway signaling and YAP/TAZCAR-T cell therapy researchImmunotherapy and Immune Responses03 medical and health sciences0302 clinical medicineAdaptor Proteins, Signal TransducingAnimalsCell Cycle ProteinsCell ProliferationCells, CulturedChemotaxis, LeukocyteDown-RegulationImmunotherapy, AdoptiveMelanoma, ExperimentalMiceMice, Inbred C57BLMice, KnockoutSkin NeoplasmsT-LymphocytesTumor MicroenvironmentYAP-Signaling Proteins

MeSH Terms

YAP-Signaling ProteinsAnimalsCells, CulturedChemotaxis, LeukocyteMelanoma, ExperimentalMice, Inbred C57BLSkin NeoplasmsT-LymphocytesDown-RegulationImmunotherapy, AdoptiveMice, KnockoutCell Cycle ProteinsAdaptor Proteins, Signal TransducingCell ProliferationMiceTumor Microenvironment

Keywords

BiologyEffectorTumor microenvironmentCancer researchCD8Cell biologyT cellHippo signaling pathwayCancer immunotherapyCytotoxic T cellCellular differentiationImmunotherapyImmunologyImmune systemIn vitroTumor cellsGeneGeneticsMice, KnockoutSkin NeoplasmsQH301-705.5T-LymphocytesMelanoma, ExperimentalDown-RegulationCell Cycle ProteinsYAP-Signaling ProteinsImmunotherapy, AdoptiveMice, Inbred C57BLChemotaxis, LeukocyteMiceShort ReportsAnimalsUMBC High Performance Computing FacilityBiology (General)Cells, CulturedAdaptor Proteins, Signal TransducingCell Proliferation

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 9 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583607.v1figshare

Additional file 9 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583607figshare

Additional file 8 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583604.v1figshare

Additional file 8 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583604figshare

Additional file 7 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583601.v1figshare

Additional file 7 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583601figshare

Additional file 6 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583598.v1figshare

Additional file 6 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583598figshare

Additional file 5 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583595.v1figshare

Additional file 5 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583595figshare

Additional file 4 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583592.v1figshare

Additional file 4 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583592figshare

Additional file 3 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583589.v1figshare

Additional file 3 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583589figshare

Additional file 2 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583586.v1figshare

Additional file 2 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583586figshare

Additional file 11 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583577.v1figshare

Additional file 11 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583577figshare

Additional file 1 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583583.v1figshare

Additional file 12 of The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

10.6084/m9.figshare.14583580.v1figshare

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Yap suppresses T-cell function and infiltration in the tumor microenvironment

FAIR Checklist

Authors (7)

Funding (7 grants)

Impact

Open Access

Topics

Linked Datasets (25)

Annotations (Europe PMC)

Related Papers (10)