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High-fidelity SaCas9 identified by directional screening in human cells

PLoS Biology(2020)10.1371/journal.pbio.3000747Source: DataRank Database

High-fidelity SaCas9 identified by directional screening in human cells is a research paper published in PLoS Biology (2020). On theSindex it has a DataRank of 0. It has been cited 58 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access58 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 2.83)OA: goldTopics (58)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (16)

Xianglian Ge,Fayu Yang ORCID,Bang Wang ORCID,Shuang Li ORCID,Jinzhi Duan ORCID

Live enrichment

PubMed:32644995 PMC:PMC7347106 OpenAlex:https://openalex.org/W3042011257

National Natural Science Foundation of China

Grant: 81201181

National Natural Science Foundation of China

Grant: 81700885

National Natural Science Foundation of China

Grant: 81670882

Intramural NIH HHS

Grant: ZIA DK075136

National Institutes of Health

Grant: 1ZIADK075136-01

Mechanisms of tRNA-mediated stress response in bacteria and eukaryotes

FWCI

2.83

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3000747&type=printable

publisherhttps://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3000747&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pbio.3000747

journalhttps://doi.org/10.1371/journal.pbio.3000747

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32644995

Fields of Study

CRISPR and Genetic EngineeringRNA and protein synthesis mechanismsInsect symbiosis and bacterial influences0301 basic medicine0303 health sciences03 medical and health sciencesBacterial ProteinsCRISPR-Associated Protein 9Gene LibraryGenetic EngineeringGenetic LociGenome, HumanHEK293 CellsHumansNucleotidesPhenotypeReproducibility of ResultsStaphylococcus aureusTranscriptional Activation

MeSH Terms

CRISPR-Associated Protein 9Bacterial ProteinsGenetic EngineeringHumansNucleotidesPhenotypeStaphylococcus aureusReproducibility of ResultsTranscriptional ActivationGene LibraryGenome, HumanGenetic LociHEK293 Cells

Keywords

BiologyCRISPRGenome editingCas9GenomeComputational biologyGuide RNAGeneticsHuman genomeGeneTranscriptional ActivationStaphylococcus aureusQH301-705.5Genome, HumanNucleotidesMethods and ResourcesReproducibility of ResultsHEK293 CellsPhenotypeBacterial ProteinsGenetic LociCRISPR-Associated Protein 9HumansBiology (General)Genetic EngineeringGene Library

Sustainable Development Goals

SDG 3: 3. Good health