Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits

PLoS Biology(2021)10.1371/journal.pbio.3001191Source: DataRank Database

Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits is a research paper published in PLoS Biology (2021). On theSindex it has a DataRank of 0. It has been cited 71 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access71 citations

Download PDF

Cite:

Linked data & code

gen pxd pdb doi

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 4.00)OA: goldTopics (82)IDs (PubMed, PMC, OpenAlex)Annotations (4)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (19)

John T. Happ,Danielle Hedeen,Ju-Fen Zhu ORCID,Jacob L. Capener ORCID,Dana Klatt Shaw ORCID

Live enrichment

PubMed:33886552 PMC:PMC8096101 OpenAlex:https://openalex.org/W3153653456

National Institutes of Health

Grant: T32HD007491

Defense Sciences Office, DARPA

Grant: HR0011-19-2-0020, HR001119S0092-FP-FP-002

National Institute of General Medical Sciences

Grant: 1R35GM133672

NIGMS NIH HHS

Grant: R35 GM133672

NCI NIH HHS

Grant: P30 CA042014

National Institutes of Health

Grant: 5T32HD007491-10

DEVELOPMENTAL BIOLOGY TRAINING PROGRAM

National Institutes of Health

Grant: 3P30CA042014-30S2

Cancer Center Support Grant

National Institutes of Health

Grant: 5R35GM133672-07

G protein-coupled receptor signaling in development and disease: Hedgehog and beyond

FWCI

4.00

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001191&type=printable

publisherhttps://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001191&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pbio.3001191

journalhttps://doi.org/10.1371/journal.pbio.3001191

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33886552

Fields of Study

Hedgehog Signaling Pathway StudiesEpigenetics and DNA MethylationGenomic variations and chromosomal abnormalities0301 basic medicine03 medical and health sciencesAnimalsAnimals, Genetically ModifiedCatalytic DomainCells, CulturedCyclic AMP-Dependent Protein Kinase Catalytic SubunitsEmbryo, NonmammalianHEK293 CellsHedgehog ProteinsHumansMiceProtein Interaction Domains and MotifsSignal TransductionSmoothened ReceptorZebrafish

MeSH Terms

Smoothened ReceptorAnimalsCells, CulturedEmbryo, NonmammalianHumansZebrafishSignal TransductionCatalytic DomainAnimals, Genetically ModifiedMiceHedgehog ProteinsProtein Interaction Domains and MotifsCyclic AMP-Dependent Protein Kinase Catalytic SubunitsHEK293 Cells

Keywords

SmoothenedBiologyCell biologyHedgehogHedgehog signaling pathwayProtein subunitSignal transductionBiochemistryGene570Biomedical and clinical sciencesEmbryo, NonmammalianLife on LandQH301-705.51.1 Normal biological development and functioningCells610Genetically ModifiedMedical and Health SciencesAnimals, Genetically ModifiedMiceRare Diseasesveterinary and food sciencesUnderpinning researchCatalytic DomainAnimalsHumansHedgehog ProteinsProtein Interaction Domains and MotifsBiology (General)Cells, CulturedZebrafishCancerAgriculturalCyclic AMP-Dependent Protein Kinase Catalytic SubunitsCulturedNonmammalianAgricultural and Veterinary SciencesNeurosciencesBiological SciencesSmoothened ReceptorBrain DisordersBrain CancerHEK293 CellsEmbryoBiochemistry and Cell BiologyGeneric health relevanceDevelopmental BiologyResearch Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Life in Land