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Evolutionary pathways to SARS-CoV-2 resistance are opened and closed by epistasis acting on ACE2

PLoS Biology(2021)10.1371/journal.pbio.3001510Source: DataRank Database

Evolutionary pathways to SARS-CoV-2 resistance are opened and closed by epistasis acting on ACE2 is a research paper published in PLoS Biology (2021). On theSindex it has a DataRank of 0. It has been cited 12 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access12 citations

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Linked data & code

refseq uniprot rrid

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 0.74)OA: goldTopics (69)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Lingli Zhou ORCID,Zhenhua Xu ORCID,Zachary Neiman ORCID,Chien‐Fu Hung ORCID,Elia J. Duh ORCID

Live enrichment

PubMed:34932561 PMC:PMC8730403 OpenAlex:https://openalex.org/W4200290511

National Institutes of Health

Grant: EY022383

National Institutes of Health

Grant: EY022683

National Institutes of Health

Grant: P30EY001765

NEI NIH HHS

Grant: R01 EY022683

NEI NIH HHS

Grant: R01 EY022383

National Institutes of Health

Grant: 3R01EY022383-01S1

Regulation of diabetic retinopathy by Nrf2

National Institutes of Health

Grant: 5P30EY001765-41

P30 Wilmer Core Grant for Vision Research

National Institutes of Health

Grant: 5R01EY022683-08

Role of Nrf2 in retinal vascularization and ROP

FWCI

0.74

Citation Percentile

0.7%

Citation Trend

2022

2023

2024

goldLicense: cc-by

journalhttps://doi.org/10.1371/journal.pbio.3001510

publisherhttps://doi.org/10.1371/journal.pbio.3001510

publisherhttps://dx.plos.org/10.1371/journal.pbio.3001510

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34932561

repositoryhttps://doaj.org/article/ef2cd11c4f3441b2be1b8c76cc620b93

Fields of Study

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesCRISPR and Genetic Engineering0301 basic medicine03 medical and health sciencesAmino AcidsAngiotensin IIAngiotensin-Converting Enzyme 2AnimalsBinding SitesCOVID-19Disease ResistanceDogsEpistasis, GeneticEvolution, MolecularGene FrequencyHumansHydrolysisMiceMutationSARS-CoV-2Spike Glycoprotein, CoronavirusVirus Attachment

MeSH Terms

Angiotensin-Converting Enzyme 2COVID-19SARS-CoV-2Amino AcidsAngiotensin IIAnimalsBinding SitesDogsEpistasis, GeneticGene FrequencyHumansHydrolysisMutationEvolution, MolecularMiceVirus AttachmentDisease ResistanceSpike Glycoprotein, Coronavirus

Keywords

BiologyEpistasisGeneticsViral evolutionVirologyGeneGenomeBinding SitesQH301-705.5SARS-CoV-2Angiotensin IIHydrolysisCOVID-19Virus AttachmentEpistasis, GeneticEvolution, MolecularMiceDogsShort ReportsGene FrequencyMutationSpike Glycoprotein, CoronavirusAnimalsHumansAngiotensin-Converting Enzyme 2Biology (General)Amino AcidsDisease Resistance

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Life in Land