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A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models

PLoS Biology(2022)10.1371/journal.pbio.3001624Source: DataRank Database

A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models is a research paper published in PLoS Biology (2022). On theSindex it has a DataRank of 0. It has been cited 20 times.

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Open Access20 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (16 grants)OA: goldTopics (12)IDs (PubMed)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (22)

Sudhir P. Deosarkar,Elaine Cadogan ORCID,Vikki Flemington,Alysha Bray,Jingwen Zhang ORCID

Live enrichment

PubMed:35617197

National Center for Advancing Translational Sciences

Grant: UH3TR000491

National Center for Advancing Translational Sciences

Grant: U01TR002383

National Institute of Child Health and Human Development

Grant: UH3TR002097

Center for Medicine, Health and Society, Vanderbilt University

Grant: UL1TR002243

National Center for Advancing Translational Sciences

Grant: HHSN271201600009C

National Center for Advancing Translational Sciences

Grant: hhsn271201700044c

National Cancer Institute

Grant: u01CA202229

Defense Threat Reduction Agency

Grant: hdtrA1-09-0013

Los Alamos National Laboratory

Grant: CBMXCEL-XL1-2-001

National Science Foundation

Grant: CBET-1706155

National Institutes of Health

Grant: 3UH3TR000491-05S2

Neurovascular Unit on a Chip: Regional Chemical Communication, Drug and Toxin Responses

National Institutes of Health

Grant: 1U01CA202229-01

Physical Dynamics of Cancer Response to Chemotherapy in 3D Microenvironments

National Institutes of Health

Grant: 5UL1TR002243-05

Vanderbilt Institute for Clinical and Translational Research (VICTR)

National Science Foundation

Grant: 1706155

A high throughput platform for the selective generation of neurons from stem cells

National Institutes of Health

Grant: 5UH3TR002097-05

Drug development for tuberous sclerosis complex and other pediatric epileptogenic diseases using neurovascular and cardiac microphysiological models

National Institutes of Health

Grant: 5U01TR002383-05

Harnessing human brain and liver microphysiological systems for testing therapeutics for metastatic melanoma

goldLicense: cc-by

publisherhttps://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001624&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pbio.3001624

repositoryhttps://www.osti.gov/biblio/1870174

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9135222

https://doi.org/10.1371/journal.pbio.3001624

Fields of Study

0301 basic medicine03 medical and health sciences

Keywords

MiceQH301-705.5MicrofluidicsMethods and ResourcesCell Culture TechniquesAnimalsHumansDNABiology (General)Models, Biological