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Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling

PLoS Biology(2024)10.1371/journal.pbio.3002673Source: DataRank Database

Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling is a research paper published in PLoS Biology (2024). On theSindex it has a DataRank of 0. It has been cited 4 times.

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Open Access4 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (7 grants)OA: goldTopics (45)IDs (PubMed, PMC)Annotations (2)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Peishen Zhao ORCID,Brian P. Cary ORCID,Xiaomeng Xu ORCID,Aditya J. Desai ORCID,Maoqing Dong ORCID

Live enrichment

PubMed:39083706 PMC:PMC11290853

National Institute of General Medical Sciences

Grant: GM141003

National Health and Medical Research Council

Grant: 2025694

National Health and Medical Research Council

Grant: 2026300

Australian Research Council

Grant: FT180100543

ARC Future Fellowships - Grant ID: FT180100543

NIDDK NIH HHS

Grant: R01 DK032878

NIGMS NIH HHS

Grant: R01 GM141003

National Institutes of Health

Grant: 1R01GM141003-01A1

Impact of membrane composition on cholecystokinin receptor structure and function

goldLicense: cc-by

publisherhttps://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002673&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pbio.3002673

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11290853/pdf/pbio.3002673.pdf

repositoryhttps://doaj.org/article/897ba52f46f9422aa4eba66be6e9d3a4

Unpaywallhttps://doi.org/10.1371/journal.pbio.3002673

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

CHO CellsAnimalsHumansCricetulusCholesterolGTP-Binding ProteinsReceptor, Cholecystokinin AReceptor, Cholecystokinin BLigandsProtein ConformationProtein BindingMutationHEK293 Cells

Keywords

2800 NeuroscienceStructural DeterminantsQH301-705.5Protein ConformationActivationSiteCHO CellsEnvironmentLigands1100 Agricultural and Biological SciencesCricetulus1300 Biochemistry, Genetics and Molecular BiologyGTP-Binding ProteinsAnimalsHumansBiology (General)Accurate2400 Immunology and MicrobiologyBeam-Induced MotionReceptor, Cholecystokinin BReceptor, Cholecystokinin ACholesterolHEK293 CellsDysfunction2Nd Intracellular LoopMutationTerminusUpdate ArticleOrganizationProtein Binding