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Expression of intron-containing HIV-1 RNA induces NLRP1 inflammasome activation in myeloid cells

PLoS Biology(2025)10.1371/journal.pbio.3003320Source: DataRank Database

Expression of intron-containing HIV-1 RNA induces NLRP1 inflammasome activation in myeloid cells is a research paper published in PLoS Biology (2025). On theSindex it has a DataRank of 0. It has been cited 4 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 2.53)OA: goldTopics (25)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

I A Hughes ORCID,Hisashi Akiyama ORCID,Aldana D. Gojanovich,Andrés A. Quiñones-Molina ORCID,Mengwei Yang ORCID

Live enrichment

PubMed:40920844 PMC:PMC12416851 OpenAlex:https://openalex.org/W4414053935

National Institute on Drug Abuse

Grant: R01DA059952

NIA NIH HHS

Grant: R01 AG060890

NIAID NIH HHS

Grant: R01 AI187175

NIDA NIH HHS

Grant: R01 DA051889

NIAID NIH HHS

Grant: P30 AI042853

NIDA NIH HHS

Grant: R01 DA055488

FWCI

2.53

Citation Percentile

0.9%

Citation Trend

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3003320&type=printable

publisherhttps://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3003320&type=printable

journalhttps://doi.org/10.1371/journal.pbio.3003320

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40920844

repositoryhttps://doaj.org/article/7387f47aac514d0c8744ceb3f6a79e5c

Fields of Study

HIV Research and TreatmentInflammasome and immune disordersReproductive System and Pregnancy

MeSH Terms

NLR ProteinsHumansImmunity, InnateIntronsMacrophagesRNA, ViralHIV-1HIV InfectionsMicrogliaMyeloid CellsAdaptor Proteins, Signal TransducingApoptosis Regulatory ProteinsInterleukin-1betaInflammasomes

Keywords

InflammasomeInnate immune systemGene knockdownMDA5MicrogliaSecretionNLRP1Macrophage