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Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes

PLoS Computational Biology(2020)10.1371/journal.pcbi.1007701Source: DataRank Database

Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes is a research paper published in PLoS Computational Biology (2020). On theSindex it has a DataRank of 0. It has been cited 52 times.

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Open Access52 citations

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Enrichment:Funding (4 grants)OA: goldTopics (46)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Junfei Zhao ORCID,Weiqiang Lü ORCID,Yao Dai,Jennifer Hockings,Yadi Zhou ORCID

Live enrichment

PubMed:32101536 PMC:PMC7062285

Foundation for the National Institutes of Health

Grant: R00HL138272

Foundation for the National Institutes of Health

Grant: HHSN261200800001E

National Natural Science Foundation of China

Grant: 61873080

National Institutes of Health

Grant: 5R00HL138272-03

An individualized network medicine infrastructure for precision cardio-oncology

goldLicense: cc-by

publisherhttps://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1007701&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pcbi.1007701

repositoryhttps://doaj.org/article/2f2cba8bf9d540278cdbc4739978b35f

repositoryhttps://figshare.com/articles/Individualized_genetic_network_analysis_reveals_new_therapeutic_vulnerabilities_in_6_700_cancer_genomes/11904765

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7062285

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

Cell Line, TumorHumansNeoplasmsBRCA2 ProteinAntineoplastic AgentsSurvival RateProtein Interaction MappingInhibitory Concentration 50Computational BiologyGenomicsPharmacogeneticsMutationModels, TheoreticalTumor Suppressor Protein p53Gene Regulatory NetworksGenetic TestingExomeCarcinogenesisCRISPR-Cas SystemsBiomarkers, TumorPrecision Medicine

Keywords

QH301-705.5CarcinogenesisAntineoplastic AgentsInhibitory Concentration 50Cell Line, TumorNeoplasmsProtein Interaction MappingBiomarkers, TumorHumansExomeGene Regulatory NetworksGenetic TestingBiology (General)Precision MedicineBRCA2 ProteinComputational BiologyGenomicsModels, TheoreticalSurvival RatePharmacogeneticsMutationCRISPR-Cas SystemsResearch Article

Sustainable Development Goals

SDG 3: 3. Good health

Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes

FAIR Checklist

Authors (9)

Funding (4 grants)

Open Access

Topics

Annotations (Europe PMC)