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Machine learning on multiple epigenetic features reveals H3K27Ac as a driver of gene expression prediction across patients with glioblastoma

PLoS Computational Biology(2025)10.1371/journal.pcbi.1012272Source: DataRank Database

Machine learning on multiple epigenetic features reveals H3K27Ac as a driver of gene expression prediction across patients with glioblastoma is a research paper published in PLoS Computational Biology (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 1.22)OA: goldTopics (48)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Hardy Bright,円杉浦 ORCID,Merih Deniz Toruner ORCID,Jordan Idehen,Nikos Tapinos ORCID

Live enrichment

PubMed:40773517 PMC:PMC12352877 OpenAlex:https://openalex.org/W4413051287

National Institute of Health

Grant: 1R35HG011939-01

Deep learning for understanding gene regulation in diseases via 'omics' integration

NHGRI NIH HHS

Grant: R35 HG011939

Honjo International Scholarship Foundation

Warren Alpert Foundation

FWCI

1.22

Citation Percentile

0.8%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1012272&type=printable

publisherhttps://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1012272&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pcbi.1012272

journalhttps://doi.org/10.1371/journal.pcbi.1012272

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40773517

Fields of Study

Epigenetics and DNA MethylationCancer-related molecular mechanisms researchCancer Genomics and DiagnosticsGlioblastomaHumansEpigenesis, GeneticMachine LearningHistonesGene Expression Regulation, NeoplasticBrain NeoplasmsComputational BiologyNeoplastic Stem CellsGene Expression Profiling

MeSH Terms

Machine LearningBrain NeoplasmsGlioblastomaHistonesHumansNeoplastic Stem CellsGene Expression Regulation, NeoplasticComputational BiologyGene Expression ProfilingEpigenesis, Genetic

Keywords

EpigeneticsBiologyReprogrammingCTCFEnhancerComputational biologyPhenotypeEpigenomicsTranscriptomeRegulation of gene expressionGene expressionGeneticsGeneDNA methylationMachine LearningHistonesGene Expression Regulation, NeoplasticBrain NeoplasmsGene Expression ProfilingNeoplastic Stem CellsHumansGlioblastomaArticleResearch ArticleEpigenesis, Genetic