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Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

PLoS Genetics(2020)10.1371/journal.pgen.1008718Source: DataRank Database

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits is a research paper published in PLoS Genetics (2020). On theSindex it has a DataRank of 0.819. It has been cited 234 times.

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0.819DataRank · unranked

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Open Access234 citations

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Enrichment:Funding (53 grants)Impact (FWCI 17.34)OA: goldTopics (131)Linked Datasets (22)DataCite Reuse (22)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (3)

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Base Score 100%Citation Network 0%

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0.819

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Authors (100)

Jonathan P. Bradfield,Tarunveer S. Ahluwalia ORCID,John A. Curtin ORCID,Timo A. Lakka ORCID,Niels Grarup ORCID

Live enrichment

PubMed:33045005 PMC:PMC7581004 OpenAlex:https://openalex.org/W3033125864

Wellcome Trust

Grant: 106130/Z/14/Z

Wellcome Trust

Grant: 202802/Z/16/Z

European Research Council

Grant: 322605

Metabolic regulation of growth and body composition: key modulators of long-term health

Medical Research Council

Grant: MC_PC_15018

Medical Research Council

Grant: MC_UU_00011/3

Statistical Methods for Improving Causal Analyses

Medical Research Council

Grant: MR/K002449/1

Medical Research Council

Grant: MRC_MC_UU_12012/5

Novo Nordisk Fonden

Grant: NNF18OC0054741

Novo Nordisk Fonden

Grant: NNF19OC0057445

Wellcome Trust

Grant: WT206194

Wellcome Trust

Grant: 090532

Understanding the genetic basis of common human diseases: core funding for the Wellcome Trust Centre for Human Genetics.

Novo Nordisk Fonden

Grant: NNF15OC0016108

Novo Nordisk Fonden

Grant: NNF16OC0021254

Novo Nordisk Fonden

Grant: NNF17OC0027492

NNF Center for Basic Metabolic Research

Grant: Pedersen Group

Steno Diabetes Center Copenhagen (SDCC)

Grant: SDCC 3.A Complications

Wellcome Trust

Grant: 106130

A systematic approach to understanding the biology underpinning GWAS hits.

Wellcome Trust

Grant: 098497/Z/12/Z

Wellcome Trust

Grant: 203141

Human Genetics and Disease Biology: Core Renewal for the Wellcome Trust Centre for Human Genetics

NNF Center for Basic Metabolic Research

Grant: Grarup Group

NNF Center for Basic Metabolic Research

Grant: Hansen Group

Medical Research Council

Grant: MC_PC_19009

Medical Research Council

Grant: MC_UU_12012/5

Medical Research Council

Grant: MC_UU_12015/1

Medical Research Council

Grant: MR/T014067/1

National Institute for Health Research (NIHR)

Grant: NF-SI-0616-10065

Novo Nordisk Fonden

Grant: NNF18OC0052457

NIDDK NIH HHS

Grant: U01 DK105535

Wellcome Trust

Grant: 104150/Z/14/Z

Wellcome Trust

Grant: 217065/Z/19/Z

Medical Research Council

Grant: G0601361

Medical Research Council

Grant: MC_UU_00011/1

Mendelian randomization to hypothesis-free causal inference

Medical Research Council

Grant: MR/K002449/2

NICHD NIH HHS

Grant: R01 HD058886

Wellcome Trust

Grant: 098395/Z/12/Z

Medical Research Council

Grant: MC_UU_12015/2

Medical Research Council

Grant: MR/S025340/1

NNF Center for Basic Metabolic Research

Grant: Phenomics

Lundbeck Foundation

Grant: R163-2013-16235

Wellcome Trust

Grant: 098381

Characterising causal alleles for common disease.

European Research Council

Grant: 648916

Embryonic origins of cardiovascular health in later life: disentangling early causal pathways in a lifecourse perspective

Medical Research Council

Grant: G9815508

Medical Research Council

Grant: MC_UU_00006/2

Wellcome Trust

Grant: WT104150

Wellcome Trust

Grant: 212259

National Institute for Health Research (NIHR)

Grant: NF-SI-0617-10090

Wellcome Trust

Grant: 206194

Wellcome Trust Sanger Institute - generic account for deposition of all core- funded research papers.

Wellcome Trust

Grant: 098497

Molecular and neural basis of obesity

Wellcome Trust

Grant: 098395

New insights from Neonatal Diabetes.

National Institutes of Health

Grant: 5R01HD058886-02

Genome Wide Association Study of Bone Mineral Accretion During Childhood

National Institutes of Health

Grant: 7U01DK105535-06

Integrating genome-scale data to reveal causal mechanisms in type 2 diabetes

European Commission

Grant: 733206

Early-life stressors and LifeCycle health

European Commission

Grant: 279153

Beta-cell function in juvenile diabetes and obesity

FWCI

17.34

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1008718&type=printable

publisherhttps://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1008718&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pgen.1008718

journalhttps://doi.org/10.1371/journal.pgen.1008718

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33045005

Fields of Study

Genetic Associations and EpidemiologyBirth, Development, and HealthEpigenetics and DNA Methylation0303 health sciences03 medical and health sciences0301 basic medicine

MeSH Terms

Nedd4 Ubiquitin Protein LigasesCardiometabolic Risk FactorsAdolescentAdultBlood PressureCardiovascular DiseasesChildChild, PreschoolDiabetes Mellitus, Type 2FemaleHumansMaleMenarcheMonosaccharide Transport ProteinsBody Mass IndexGenetic Predisposition to DiseaseWaist-Hip RatioGenome-Wide Association StudyMendelian Randomization Analysis

Keywords

Body mass indexHeritabilityChildhood obesityBiologyTwin studyMenarcheGenome-wide association studyObesityGeneticsDemographyOverweightEndocrinologyGenotypeSingle-nucleotide polymorphismGeneMaleGenetic-variationNedd4 Ubiquitin Protein LigasesSustainable Development GoalsPooled AnalysisBlood Pressure7961105 Ecology3121PreescolarAnálisis de la Aleatorización MendelianaHuman geneticsMendelian RandomizationGenetics(clinical)1306 Cancer ResearchMasculinoChildAdolescenteSDG 3AdiposityGenetics & HeredityadultCARDIOVASCULAR RISKHumanos[SDV] Life Sciences [q-bio]Physical sciencesCardiovascular DiseasesChild, PreschoolcardiometabolicType 2570Monosaccharide Transport ProteinsEvolutionGenetic lociProstate-specific Antigen610Predisposición Genética a la Enfermedad1311 GeneticsSDG 3 - Good Health and Well-beingDiabetes Mellitus1312 Molecular BiologyHumansGENOME-WIDE ASSOCIATIONPresión SanguíneaMolecular BiologyMedicine and health sciences[SDV.GEN]Life Sciences [q-bio]/GeneticsScience & TechnologyEarly Growth Genetics ConsortiumSingle nucleotide polymorphismsta3121Mendelian Randomization Analysisname=SDG 3 - Good Health and Well-beingDiabetes Mellitus, Type 2MenarquiaEMC MM-04-54-08-AÍndice de Masa CorporalCancer Research[SDV.GEN] Life Sciences [q-bio]/GeneticsFactores de Riesgo CardiometabólicoDiabetes Mellitus Tipo 2QH426-470Genome-wide association studiesYOUNG-ADULTSGenetics of diseaseEnfermedades CardiovascularesEcologyAdultoFemeninoMetaanalysisWessex Classification Subject Headings::Endocrinology::DiabetesUbiquitina-Proteína Ligasas Nedd4Niño/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleLife Sciences & BiomedicineResearch Article2716 Genetics (clinical)AdolescentAdipose tissueFOS: Physical sciencesEstudio de Asociación del Genoma CompletoBehavior and SystematicsProteínas de Transporte de MonosacáridosGenetic Predisposition to DiseasePreschoolBiology and life sciencesWaist-Hip RatioCardiometabolic Risk FactorsResearch and analysis methodsRelación Cintura-Cadera

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 2 of Genomic correlation, shared loci, and causal relationship between obesity and polycystic ovary syndrome: a large-scale genome-wide cross-trait analysis

10.6084/m9.figshare.19159186.v1figshare

Additional file 2 of Genomic correlation, shared loci, and causal relationship between obesity and polycystic ovary syndrome: a large-scale genome-wide cross-trait analysis

10.6084/m9.figshare.19159186figshare

Additional file 1 of Your height affects your health: genetic determinants and health-related outcomes in Taiwan

10.6084/m9.figshare.20308036.v1figshare

Additional file 1 of Your height affects your health: genetic determinants and health-related outcomes in Taiwan

10.6084/m9.figshare.20308036figshare

Additional file 2 of Your height affects your health: genetic determinants and health-related outcomes in Taiwan

10.6084/m9.figshare.20308042.v1figshare

Additional file 2 of Your height affects your health: genetic determinants and health-related outcomes in Taiwan

10.6084/m9.figshare.20308042figshare

Additional file 3 of Your height affects your health: genetic determinants and health-related outcomes in Taiwan

10.6084/m9.figshare.20308048.v1figshare

Additional file 3 of Your height affects your health: genetic determinants and health-related outcomes in Taiwan

10.6084/m9.figshare.20308048figshare

Additional file 4 of Your height affects your health: genetic determinants and health-related outcomes in Taiwan

10.6084/m9.figshare.20308054.v1figshare

Additional file 4 of Your height affects your health: genetic determinants and health-related outcomes in Taiwan

10.6084/m9.figshare.20308054figshare

Additional file 5 of Your height affects your health: genetic determinants and health-related outcomes in Taiwan

10.6084/m9.figshare.20308060.v1figshare

Additional file 5 of Your height affects your health: genetic determinants and health-related outcomes in Taiwan

10.6084/m9.figshare.20308060figshare

Additional file 1 of Childhood obesity and risk of Alzheimer’s disease: a Mendelian randomization study

10.6084/m9.figshare.25434151.v1figshare

Additional file 1 of Childhood obesity and risk of Alzheimer’s disease: a Mendelian randomization study

10.6084/m9.figshare.25434151figshare

Additional file 2 of Metabolome-wide Mendelian randomization for age at menarche and age at natural menopause

10.6084/m9.figshare.25910090.v1figshare

Additional file 2 of Metabolome-wide Mendelian randomization for age at menarche and age at natural menopause

10.6084/m9.figshare.25910090figshare

Additional file 1 of Tri-ponderal mass index and left ventricular hypertrophy in a cohort of caucasian children and adolescents with obesity

10.6084/m9.figshare.26708768.v1figshare

Additional file 1 of Tri-ponderal mass index and left ventricular hypertrophy in a cohort of caucasian children and adolescents with obesity

10.6084/m9.figshare.26708768figshare

Additional file 1 of Metabolome-wide Mendelian randomization for age at menarche and age at natural menopause

10.6084/m9.figshare.25909997.v1figshare

Additional file 1 of Metabolome-wide Mendelian randomization for age at menarche and age at natural menopause

10.6084/m9.figshare.25909997figshare

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Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

FAIR Checklist

DataRank Breakdown

Authors (100)

Funding (53 grants)

Impact

Open Access

Topics

Linked Datasets (22)

Annotations (Europe PMC)

Related Papers (10)