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Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer’s dementia

PLoS Genetics(2021)10.1371/journal.pgen.1009482Source: DataRank Database

Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer’s dementia is a research paper published in PLoS Genetics (2021). On theSindex it has a DataRank of 0. It has been cited 82 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access82 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 5.48)OA: goldTopics (28)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Aron S. Buchman ORCID,Philip L. De Jager ORCID,David A. Bennett ORCID,Michael P. Epstein ORCID,Jingjing Yang ORCID

Live enrichment

PubMed:33798195 OpenAlex:https://openalex.org/W3144882087

National Institute of General Medical Sciences

Grant: R35GM138313

National Institute of General Medical Sciences

Grant: R01GM117946

National Institute on Aging

Grant: RF1AG071170

National Institute on Aging

Grant: P30AG10161, R01AG15819, R01AG17917, R01AG30146, R01AG36836, R01AG56352, U01AG32984, U01AG46152, U01AG61356

FWCI

5.48

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1371/journal.pgen.1009482

publisherhttps://doi.org/10.1371/journal.pgen.1009482

publisherhttps://dx.plos.org/10.1371/journal.pgen.1009482

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33798195

repositoryhttps://doaj.org/article/0db898beb477413fa2ca281726297f7e

Fields of Study

Bioinformatics and Genomic NetworksGenetic Associations and EpidemiologyGene expression and cancer classification

MeSH Terms

Mitochondrial Precursor Protein Import Complex ProteinsAlzheimer DiseaseDementiaFemaleGene Expression RegulationHumansMaleGenetic Predisposition to DiseasePolymorphism, Single NucleotideMembrane Transport ProteinsGenome-Wide Association StudyTranscriptome

Keywords

Expression quantitative trait lociGenome-wide association studyBiologyComputational biologyTranscriptomeSingle-nucleotide polymorphismMultiple comparisons problemGeneticsGeneStatisticsGene expressionMathematicsGenotype