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Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index

PLoS Genetics(2022)10.1371/journal.pgen.1010093Source: DataRank Database

Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index is a research paper published in PLoS Genetics (2022). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Enrichment:Funding (21 grants)OA: goldTopics (57)IDs (PubMed, PMC)Annotations (1)SDGs (2)

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Authors (26)

John Dominy ORCID,Shareef Khalid,Linh Vong,Shari L. Caplan ORCID,Treeve Currie

Live enrichment

PubMed:35381001 PMC:PMC9022822

National Institutes of Health

Grant: R01-HL-145437

National Institutes of Health

Grant: R01-HG-010689

National Institutes of Health

Grant: R01-HL133339

National Institutes of Health

Grant: X01HL139399

National Institutes of Health

Grant: RC2 HL101834-01

National Institutes of Health

Grant: RC1 TW008485-01

FIC NIH HHS

Grant: RC1 TW008485

British Heart Foundation

Grant: CH/12/2/29428

British Heart Foundation

Grant: RG/13/13/30194

Medical Research Council

Grant: HDR-9004

NHGRI NIH HHS

Grant: R01 HG010689

NHLBI NIH HHS

Grant: R01 HL133339

NHLBI NIH HHS

Grant: R01 HL145437

NHLBI NIH HHS

Grant: RC2 HL101834

British Heart Foundation

Grant: RG/18/13/33946

National Institutes of Health

Grant: 5R01HG010689-02

Leveraging consanguinity and homozygosity to identify novel recessive variants

National Institutes of Health

Grant: 7R01AI139399-04

Particulate-based in vivo modulation for immunotherapy of Rheumatoid Arthritis

National Institutes of Health

Grant: 1RC2HL101834-01

Comprehensive biomarker study to capitalize on existing GWAS in 10K South Asians

National Institutes of Health

Grant: 5R01HL145437-02

Deep Phenotyping of ANGPTL3, ANGPTL4 and ANGPTL8 Human Knockouts and Population Based Studies

National Institutes of Health

Grant: 5RC1TW008485-02

Markers of the metabolic syndrome linking type 2 diabetes and MI in South Asia

National Institutes of Health

Grant: 5R01HL133339-02

Deep Phenotyping of Human Knockouts and Population Studies of the APOC3 Pathway

goldLicense: CC BY

publisherhttps://dx.plos.org/10.1371/journal.pgen.1010093

Europe_PMChttps://europepmc.org/articles/PMC9022822

Europe_PMChttps://europepmc.org/articles/PMC9022822?pdf=render

https://doi.org/10.1371/journal.pgen.1010093

https://dx.doi.org/10.17863/cam.83756

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsHumansMiceDiabetes Mellitus, Type 2ObesityReceptors, G-Protein-CoupledBody Mass IndexGene FrequencyExome

Keywords

Exome sequencingWeight lossEndocrinology, Diabetes and MetabolismEngineering and technologyQH426-470GeneGene knockoutBody Mass IndexReceptors, G-Protein-CoupledMiceEndocrinologyDiabetes mellitusGene FrequencyStructure and Function of G Protein-Coupled ReceptorsExomeInternal medicineAlleleManagement of Diabetes Mellitus and Cardiovascular RiskLife SciencesType 2 diabetesLoss functionRole of Neuropeptides in Physiology and DiseasePhysical sciencesPhenotypeMedicineResearch ArticleFOS: Physical sciencesCellular and Molecular NeuroscienceBiochemistry, Genetics and Molecular BiologyHealth SciencesGeneticsAnimalsHumansObesityMolecular BiologyBiologyMedicine and health sciencesBiology and life sciencesG Protein-Coupled ReceptorsFOS: Engineering and technologyGlucose ControlResearch and analysis methodsDiabetes Mellitus, Type 2FOS: Biological sciencesNeuroscience

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 3: 3. Good health

Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index

FAIR Checklist

Authors (26)

Funding (21 grants)

Open Access

Topics

Annotations (Europe PMC)