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The transcription factors Tfeb and Tfe3 are required for survival and embryonic development of pancreas and liver in zebrafish

PLoS Genetics(2025)10.1371/journal.pgen.1011754Source: DataRank Database

The transcription factors Tfeb and Tfe3 are required for survival and embryonic development of pancreas and liver in zebrafish is a research paper published in PLoS Genetics (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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Enrichment:Funding (3 grants)Impact (FWCI 4.12)OA: goldTopics (44)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Martina La Spina ORCID,Erica Bresciani ORCID,Zulfeqhar A. Syed ORCID,Christian A. Combs ORCID,Martha Kirby ORCID

Live enrichment

PubMed:40577485 PMC:PMC12225984 OpenAlex:https://openalex.org/W4411724747

NHLBI Division of Intramural Research

Grant: ZIA HL006075-15

Intramural NIH HHS

Grant: ZIA HL006075

National Institutes of Health

Grant: 1ZIAHL006075-05

Role of endolysosomal channels in calcium homeostasis and trafficking

FWCI

4.12

Citation Percentile

0.9%

Citation Trend

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011754&type=printable

GOLDhttps://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011754&type=printable

publisherhttps://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011754&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pgen.1011754

journalhttps://doi.org/10.1371/journal.pgen.1011754

Fields of Study

Pancreatic function and diabetesAutophagy in Disease and TherapyMicroRNA in disease regulationMedicineBiology0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsAutophagyLiverPancreasZebrafishApoptosisOxidative StressGene Expression Regulation, DevelopmentalZebrafish ProteinsEmbryonic DevelopmentBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCRISPR-Cas Systems

Keywords

TFEBBiologyZebrafishCell biologyPancreasAutophagyTranscription factorProteotoxicityPAX6Cancer researchEndocrinologyGeneticsGeneApoptosisProtein aggregationBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsEmbryonic DevelopmentGene Expression Regulation, DevelopmentalQH426-470Zebrafish ProteinsOxidative StressLiverAnimalsCRISPR-Cas SystemsResearch Article

Sustainable Development Goals

SDG 0: Affordable and clean energy

The transcription factors Tfeb and Tfe3 are required for survival and embryonic development of pancreas and liver in zebrafish

FAIR Checklist

Authors (11)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)