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Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2

PLoS Genetics(2025)10.1371/journal.pgen.1011780Source: DataRank Database

Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2 is a research paper published in PLoS Genetics (2025). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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Enrichment:Funding (6 grants)Impact (FWCI 3.45)OA: goldTopics (50)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Irini Topalidou ORCID,Nicolas J. Lehrbach ORCID,Briar Jochim

Live enrichment

PubMed:40623109 PMC:PMC12251208 OpenAlex:https://openalex.org/W4412072840

National Institute of General Medical Sciences

Grant: R35GM142728

Fred Hutch/University of Washington/Seattle Children’s Cancer Consortium

Grant: P30 CA015704

NIH HHS

Grant: P40 OD010440

National Institutes of Health

Grant: 1P40OD010440-01

Caenorhabditis Genetics Center

National Institutes of Health

Grant: 3P30CA015704-42S2

Cancer Center Support Grant

National Institutes of Health

Grant: 5R35GM142728-05

Regulation of Proteasome Capacity

FWCI

3.45

Citation Percentile

0.9%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011780&type=printable

GOLDhttps://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011780&type=printable

publisherhttps://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011780&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pgen.1011780

journalhttps://doi.org/10.1371/journal.pgen.1011780

Fields of Study

Genomics, phytochemicals, and oxidative stressGenetics, Aging, and Longevity in Model OrganismsCoenzyme Q10 studies and effectsMedicineBiologyChemistry0301 basic medicine03 medical and health sciencesCaenorhabditis elegans ProteinsAnimalsCaenorhabditis elegansTranscription FactorsDNA-Binding ProteinsOxidative StressNF-E2-Related Factor 2Proteasome Endopeptidase ComplexNF-E2-Related Factor 1

MeSH Terms

AnimalsDNA-Binding ProteinsTranscription FactorsCaenorhabditis elegansOxidative StressCaenorhabditis elegans ProteinsProteasome Endopeptidase ComplexNF-E2-Related Factor 1NF-E2-Related Factor 2

Keywords

BiologyProteostasisNRF1Cell biologyProtein subunitProteasomeConserved sequenceGeneBiochemistryGeneticsTranscription factorPeptide sequenceProteasome Endopeptidase ComplexNF-E2-Related Factor 2NF-E2-Related Factor 1QH426-470ArticleDNA-Binding ProteinsOxidative StressAnimalsCaenorhabditis elegans ProteinsCaenorhabditis elegansResearch ArticleTranscription Factors

Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2

FAIR Checklist

Authors (3)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)