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The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population

PLoS Medicine(2020)10.1371/journal.pmed.1003196Source: DataRank Database

The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population is a research paper published in PLoS Medicine (2020). On theSindex it has a DataRank of 0. It has been cited 88 times.

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Open Access88 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)OA: goldTopics (57)IDs (PubMed)SDGs (2)

FAIR Checklist

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Michael Preuß ORCID,Ryan W. Walker ORCID,Arden Moscati ORCID,Ruth J. F. Loos ORCID,Nathalie Chami ORCID

Live enrichment

PubMed:32692746

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01DK110113

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01DK124097

University of Copenhagen (Denmark), NNF Center for Basic Metabolic Research

Grant: Alliance Award

National Institutes of Health

Grant: 1R01DK110113-01

Study of coding variants in human obesity and their functional characterization using human iPSC-derived cellular models

National Institutes of Health

Grant: 1R01DK124097-01A1

Resilience to obesity in carriers of monogenic obesity mutations - a study on the underlying mechanisms

Canadian Institutes of Health Research

Grant: unidentified

unidentified

Medical Research Council

Grant: MC_QA137853

NIDDK NIH HHS

Grant: P30 DK020541

Medical Research Council

Grant: MC_PC_17228

CIHR

goldLicense: cc-by

publisherhttps://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1003196&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pmed.1003196

repositoryhttps://doaj.org/article/c4222780c7f04788be1d3fd9bddefd3a

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7373259

https://doi.org/10.1371/journal.pmed.1003196

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciencesAdultAgedBiological Specimen BanksBody CompositionBody Mass IndexBody WeightFemaleGenetic Predisposition to DiseaseHeterozygoteHumansMaleMiddle AgedMutationObesityPenetranceReceptor, Melanocortin, Type 4United Kingdom

MeSH Terms

AdultAgedBiological Specimen BanksBody CompositionBody Mass IndexBody WeightFemaleGenetic Predisposition to DiseaseHeterozygoteHumansMaleMiddle AgedMutationObesityPenetranceReceptor, Melanocortin, Type 4United Kingdom

Keywords

AdultMaleHeterozygoteBody WeightRPenetranceMiddle AgedUnited KingdomBody Mass IndexMutationBody CompositionMedicineHumansReceptor, Melanocortin, Type 4FemaleGenetic Predisposition to DiseaseObesityResearch ArticleAgedBiological Specimen Banks

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 3: 3. Good health