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Immune exhaustion in chronic Chagas disease: Pro-inflammatory and immunomodulatory action of IL-27 in vitro

PLoS neglected tropical diseases(2021)10.1371/journal.pntd.0009473Source: DataRank Database

Immune exhaustion in chronic Chagas disease: Pro-inflammatory and immunomodulatory action of IL-27 in vitro is a research paper published in PLoS neglected tropical diseases (2021). On theSindex it has a DataRank of 0. It has been cited 8 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access8 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 0.71)OA: goldTopics (62)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Todd Minning ORCID,María C. Albareda ORCID,Melisa D. Castro Eiro ORCID,M Alvarez ORCID,Bruno Lococo

Live enrichment

PubMed:34061845 PMC:PMC8195349 OpenAlex:https://openalex.org/W3164464383

National Institutes of Health/National Institute of Allergy and Infectious Diseases

Grant: 143496

NIAID NIH HHS

Grant: R01 AI143496

National Institutes of Health

Grant: 5R01AI143496-02

Correlates of innate and T-cell immunity in seropositive and serodiscordant subjects for Trypanosoma cruzi infection.

CONICET

Ministry of Health of the Province of Buenos Aires, Argentina

National Ministry of Health of Argentina

FWCI

0.71

Citation Percentile

0.7%

Citation Trend

2022

2023

2024

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0009473&type=printable

publisherhttps://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0009473&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pntd.0009473

journalhttps://doi.org/10.1371/journal.pntd.0009473

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34061845

Fields of Study

Trypanosoma species research and implicationsResearch on Leishmaniasis StudiesWhipple's Disease and Interleukins03 medical and health sciences0302 clinical medicine

MeSH Terms

AdultAgedChronic DiseaseFemaleHumansLeukocytes, MononuclearMaleMiddle AgedTrypanosoma cruziChagas DiseaseInterleukin-7Receptors, InterleukinCD8-Positive T-LymphocytesSTAT3 Transcription FactorInterleukin-27

Keywords

ImmunologyImmune systemDownregulation and upregulationChagas diseaseBiologyCytokineInflammationT cellAdultMaleSTAT3 Transcription FactorInterleukin-27EpidemiologyEpidemiology and Treatment of Chagas DiseaseTrypanosoma cruziRC955-962CD8-Positive T-LymphocytesBiochemistryGeneGlobal Burden of Leishmaniasis Incidence and TreatmentT CRUZIPathology and Forensic Medicinehttps://purl.org/becyt/ford/3.3Arctic medicine. Tropical medicineHealth SciencesHumanshttps://purl.org/becyt/ford/3Pathogenesis and Treatment of Whipple's DiseaseAgedInterleukin-7FOS: Clinical medicineLINFOCITOS TPublic Health, Environmental and Occupational HealthReceptors, InterleukinMiddle AgedChronic DiseaseLeukocytes, MononuclearMedicineFemalePublic aspects of medicineRA1-1270Research Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being