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Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells

PLoS neglected tropical diseases(2022)10.1371/journal.pntd.0010074Source: DataRank Database

Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells is a research paper published in PLoS neglected tropical diseases (2022). On theSindex it has a DataRank of 0. It has been cited 5 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access5 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (23 grants)Impact (FWCI 0.73)OA: goldTopics (67)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Kayla J. Rayford ORCID,Ayorinde Cooley ORCID,Tanu Rana ORCID,Girish Rachakonda ORCID,Fernando Villalta ORCID

Live enrichment

PubMed:34986160 PMC:PMC8730400 OpenAlex:https://openalex.org/W4206408183

National Institute of Allergy and Infectious Diseases

Grant: 1SC1AI127352

National Institutes of Health

Grant: 2T32AI007281-31

Molecular Microbial Pathogenesis Training Program

National Institutes of Health

Grant: 2T32HL007737-26

Research Training in Cardiovascular Biology at Meharry

National Institutes of Health

Grant: 5R25GM059994

National Institutes of Health

Grant: F31AI167579

National Institutes of Health

Grant: U54MD007586

National Institutes of Health

Grant: P30 EY016665

National Institutes of Health

Grant: P30 CA014520

National Institutes of Health

Grant: R01 EY026078

NIGMS NIH HHS

Grant: R25 GM059994

NHLBI NIH HHS

Grant: T32 HL007737

NIAID NIH HHS

Grant: SC1 AI127352

NIAID NIH HHS

Grant: T32 AI007281

National Institutes of Health

Grant: 5F31AI167579-02

Molecular mechanisms of Trypanosoma cruzi induced colon pathogenesis

National Institutes of Health

Grant: 3U54MD007586-34S3

The RCMI Program in Health Disparities Research at Meharry Medical College (Supplement)

National Institutes of Health

Grant: 5P30EY016665-15

Core Grant for Vision Research

National Institutes of Health

Grant: 1S15AI027352-01

SMALL INSTRUMENTATION PROGRAM

National Institutes of Health

Grant: 5R25GM059994-16

RISE Option III The Meharry RISE Initiative

National Institutes of Health

Grant: 5R01EY026078-04

Investigating oxygen metabolism in diabetic retinopathy

National Institutes of Health

Grant: 5SC1AI127352-02

Molecular mechanisms of Trypanosoma cruzi cardiopathogenesis

National Institutes of Health

Grant: 5P30CA014520-18

CANCER CENTER SUPPORT

RPB Stein Innovation Award

School of Medicine and Public Health, University of Wisconsin-Madison

FWCI

0.73

Citation Percentile

0.7%

Citation Trend

2022

2024

2025

goldLicense: cc-by

journalhttps://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0010074&type=printable

publisherhttps://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0010074&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pntd.0010074

journalhttps://doi.org/10.1371/journal.pntd.0010074

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34986160

Fields of Study

Trypanosoma species research and implications0301 basic medicine03 medical and health sciences0303 health sciencesActive Transport, Cell NucleusAnimalsChagas DiseaseEndothelial CellsEndotheliumGlycogen Synthase Kinase 3 betaHeartHippo Signaling PathwayMiceMice, KnockoutRatsThrombospondin 1Trypanosoma cruziWnt Signaling PathwayWnt-5a ProteinYAP-Signaling Proteinsbeta Catenin

MeSH Terms

Glycogen Synthase Kinase 3 betaWnt-5a ProteinHippo Signaling PathwayYAP-Signaling ProteinsAnimalsEndotheliumHeartTrypanosoma cruziChagas DiseaseMice, KnockoutThrombospondin 1Active Transport, Cell NucleusEndothelial Cellsbeta CateninMiceRatsWnt Signaling Pathway

Keywords

Trypanosoma cruziCell biologyWnt signaling pathwayBiologySignal transductionChagas diseaseThrombospondinHippo signaling pathwayImmunologyParasite hostingGeneticsRC955-962Active Transport, Cell NucleusWnt-5a ProteinThrombospondin 1MiceArctic medicine. Tropical medicineAnimalsEndotheliumbeta CateninMice, KnockoutGlycogen Synthase Kinase 3 betaEndothelial CellsHeartYAP-Signaling ProteinsRatsPublic aspects of medicineRA1-1270Research Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being