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Distinct Licensing of IL-18 and IL-1β Secretion in Response to NLRP3 Inflammasome Activation

PLoS ONE(2012)10.1371/journal.pone.0045186Source: DataRank Database

Distinct Licensing of IL-18 and IL-1β Secretion in Response to NLRP3 Inflammasome Activation is a research paper published in PLoS ONE (2012). On theSindex it has a DataRank of 4.0. It has been cited 106 times, with 95 citing works in its 1-hop citation network.

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4.0DataRank · unranked

Scored on demand from live citation data

106 citations · 95 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (11 grants)OA: goldTopics (44)Linked Datasets (8)DataCite Reuse (8)IDs (PubMed, PMC)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (0/2)

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 18%Citation Network 82%

Base Score Contribution

0.701

From this paper's citation signal

Citation Network Contribution

3.3

From 80 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 95 citers.

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Innate Immunity201923 citations21 referencesContributes 0.151
Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1β
The Journal of Immunology2017134 citations42 referencesContributes 0.117
PARK2 attenuates house dust mite-induced inflammatory reaction, pyroptosis and barrier dysfunction in BEAS-2B cells by ubiquitinating NLRP3.
PubMed202128 citations29 referencesContributes 0.116
Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies
Journal of Clinical Investigation2013229 citations50 referencesContributes 0.109
Multivalent Presentation of MPL by Porous Silicon Microparticles Favors T Helper 1 Polarization Enhancing the Anti-Tumor Efficacy of Doxorubicin Nanoliposomes
PLoS ONE201427 citations33 referencesContributes 0.101

Authors (2)

Laurel L. Lenz,Rebecca L. Schmidt

Live enrichment

PubMed:23028835 PMC:PMC3445464

NIAID NIH HHS

Grant: R21 AI055701

NIAID NIH HHS

Grant: T32 AI074491

NIAID NIH HHS

Grant: R01 AI065638

NIAID NIH HHS

Grant: AI055701

NIAID NIH HHS

Grant: T32-AI-074491

NIAID NIH HHS

Grant: AI065638

NIAID NIH HHS

Grant: R01 AI055701

NIAID NIH HHS

Grant: R56 AI065638

National Institutes of Health

Grant: 5R01AI065638-05

Immune Modulation by Bacterial Autolysins

National Institutes of Health

Grant: 5T32AI074491-12

Molecular Mechanisms of Immune Tolerance

National Institutes of Health

Grant: 5R01AI055701-03

CD8 Mediated Apoptosis During T Cell Development

goldLicense: cc-by

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0045186&type=printable

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/3445464

repositoryhttps://doaj.org/article/02e6d419abd14e099be3524052466c63

repositoryhttps://figshare.com/articles/dataset/Distinct_Licensing_of_IL_18_and_IL_1_Secretion_in_Response_to_NLRP3_Inflammasome_Activation/120035

Europe_PMChttps://europepmc.org/articles/PMC3445464

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

Dendritic CellsAnimalsMice, KnockoutMiceListeria monocytogenesReactive Oxygen SpeciesCaspasesCaspase 1Bacterial ProteinsCarrier ProteinsInterleukin-18Signal TransductionCell DeathGene ExpressionInterleukin-1betaCaspases, InitiatorInflammasomesNLR Family, Pyrin Domain-Containing 3 Protein

Keywords

InflammasomesScienceInterleukin-1betaGene ExpressionMiceBacterial ProteinsNLR Family, Pyrin Domain-Containing 3 ProteinAnimalsMice, KnockoutCell DeathQCaspase 1RInterleukin-18Dendritic CellsListeria monocytogenesCaspases, InitiatorCaspasesMedicineCarrier ProteinsReactive Oxygen SpeciesResearch ArticleSignal Transduction

Additional file 4 of Role of caspase-11 non-canonical inflammasomes in retinal ischemia/reperfusion injury

10.6084/m9.figshare.27123715.v1figshare

Additional file 3 of Role of caspase-11 non-canonical inflammasomes in retinal ischemia/reperfusion injury

10.6084/m9.figshare.27123712.v1figshare

Additional file 1 of Role of caspase-11 non-canonical inflammasomes in retinal ischemia/reperfusion injury

10.6084/m9.figshare.27123706.v1figshare

Additional file 1 of Role of caspase-11 non-canonical inflammasomes in retinal ischemia/reperfusion injury

10.6084/m9.figshare.27123706figshare

Additional file 2 of Role of caspase-11 non-canonical inflammasomes in retinal ischemia/reperfusion injury

10.6084/m9.figshare.27123709figshare

Additional file 4 of Role of caspase-11 non-canonical inflammasomes in retinal ischemia/reperfusion injury

10.6084/m9.figshare.27123715figshare